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USA Cruises Starting In September 2025

If you're looking at joining a cruise up and down the east and west coasts of the US in September 2025, we have 18 unique cruises with 125 departures from the world's leading cruise lines departing in September.
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Departures (September 2025)
< August 2025 October 2025 >
Duration
4 Days
21 Days
Regions
Start & End Cities
Ship Size
Ship Features
Cruise Lines
Price
$200pp
$30,995pp
Countries
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18 Cruises (125 Cruise Departures)
12 Day Classic California Coast with Princess
Cruise
 (1)

12 Days (11 Nights) Vancouver to Vancouver
Cruise Line: Princess
Ship: Coral Princess
Departure: 24 September 2025
Countries Visited: Canada, USA
INSIDE
$2,497
OCEANVIEW
$2,708
BALCONY
$2,911
SUITE
$3,412
From 2,497
View Trip
9 Day Pacific Coast Explorer with Viking Cruises
Cruise
 (4)

9 Days (8 Nights) Los Angeles to Vancouver
Cruise Line: Viking Cruises
Ship: Viking Sea
Departures: Apr 2025 to Apr 2026
Countries Visited: USA, Canada
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$4,945
SUITE
$9,400
Save 1,068
From 4,945
View Trip
9 Day Pacific Coast Explorer with Viking Cruises
Cruise
 (4)

9 Days (8 Nights) Vancouver to Los Angeles
Cruise Line: Viking Cruises
Ship: Viking Sea
Departures: Apr 2025 to Apr 2026
Countries Visited: Canada, USA
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$5,242
SUITE
$9,895
Save 1,065
From 5,242
View Trip
8 Day Pacific Wine Country with Princess
Cruise
 (4)

8 Days (7 Nights) Vancouver to Los Angeles
Cruise Line: Princess
Ship: Royal Princess
Departure: 27 September 2025
Countries Visited: Canada, USA
INSIDE
$1,270
OCEANVIEW
-
BALCONY
$1,618
SUITE
$2,101
From 1,270
View Trip
7 Day Pacific Coastal Cruise with Holland America
Cruise

7 Days (6 Nights) Vancouver to San Diego
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 28 September 2025
Countries Visited: Canada, USA
Have It All Offer
INSIDE
$1,788
OCEANVIEW
$2,036
BALCONY
$2,432
SUITE
$4,016
From 1,788
View Trip
8 Day Pacific Wine Country with Princess
Cruise

8 Days (7 Nights) Vancouver to Los Angeles
Cruise Line: Princess
Ship: Caribbean Princess
Departure: 23 September 2025
Countries Visited: Canada, USA
INSIDE
$1,293
OCEANVIEW
$1,445
BALCONY
$1,907
SUITE
$2,214
From 1,293
View Trip
8 Day Great Lakes Explorer with Viking Cruises
Cruise

8 Days (7 Nights) Milwaukee to Thunder Bay
Cruise Line: Viking Cruises
Ships: Viking Octantis, Viking Polaris
Departures: Jun 2024 to Sep 2025
Countries Visited: USA, Canada
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$9,004
SUITE
$13,855
Save 1,230
From 9,004
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) Los Angeles to Los Angeles
Cruise Line: Royal Caribbean
Ships: Navigator of the Seas, Navigator of the Seas (+1 more), Quantum of the Seas
Departures: May 2024 to Apr 2026
Countries Visited: USA, Mexico
Exclusive Deal
INSIDE
$575
OCEANVIEW
$657
BALCONY
$651
SUITE
$1,159
Save 899
From 538
View Trip
8 Day Niagara & the Great Lakes with Viking Cruises
Cruise

8 Days (7 Nights) Milwaukee to Toronto
Cruise Line: Viking Cruises
Ships: Viking Octantis, Viking Polaris
Departures: Sep 2024 to Oct 2026
Countries Visited: USA, Canada
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$8,905
SUITE
$12,865
Save 1,160
From 8,905
View Trip
6 Day Pacific Coastal Cruise with Holland America
Cruise

6 Days (5 Nights) Vancouver to San Diego
Cruise Line: Holland America
Ships: Nieuw Amsterdam, Zaandam
Departures: Sep 2024 to Sep 2025
Countries Visited: Canada, USA
Exclusive Deal
INSIDE
$795
OCEANVIEW
$894
BALCONY
$1,074
SUITE
$1,490
From 795
View Trip
8 Day Undiscovered Great Lakes with Viking Cruises
Cruise

8 Days (7 Nights) Thunder Bay to Milwaukee
Cruise Line: Viking Cruises
Ships: Viking Octantis, Viking Polaris
Departures: Jun 2024 to Sep 2025
Countries Visited: Canada, USA
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$9,004
SUITE
$13,855
Save 1,300
From 9,004
View Trip
21 Day Mexican Riviera, California And Pacific Coast with Holland America
Cruise

21 Days (20 Nights) Vancouver to San Diego
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 28 September 2025
Countries Visited: Canada, USA, Mexico
Have It All Offer
INSIDE
$5,066
OCEANVIEW
$5,561
BALCONY
$6,551
SUITE
$10,115
From 5,066
View Trip
14 Day Mexican Riviera & Pacific Coast with Holland America
Cruise

14 Days (13 Nights) Vancouver to San Diego
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 28 September 2025
Countries Visited: Canada, USA, Mexico
Have It All Offer
INSIDE
$3,154
OCEANVIEW
$3,451
BALCONY
$4,045
SUITE
$6,124
From 3,154
View Trip
12 Day Inside Passage with Glacier Bay National Park with Princess
Cruise

12 Days (11 Nights) San Francisco to San Francisco
Cruise Line: Princess
Ships: Crown Princess, Ruby Princess
Departures: Aug 2024 to Sep 2025
Countries Visited: USA, Canada
INSIDE
$1,775
OCEANVIEW
$2,231
BALCONY
$3,185
SUITE
$4,231
From 1,775
View Trip
13 Day Eastern Seaboard Explorer with Viking Cruises
Cruise
 (4)

13 Days (12 Nights) New York to Montreal
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Sep 2024 to Sep 2026
Countries Visited: USA, Canada
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$9,895
SUITE
$16,825
Save 1,155
From 9,895
View Trip
15 Day Canada & East Coast Explorer with Viking Cruises
Cruise

15 Days (14 Nights) Toronto to Fort Lauderdale
Cruise Line: Viking Cruises
Ships: Viking Octantis, Viking Polaris
Departures: Oct 2024 to Sep 2025
Countries Visited: Canada, USA
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$13,855
SUITE
$19,300
Save 1,140
From 13,855
View Trip
8 Day Canada & New England - Boston with Norwegian Cruise Line
Cruise

8 Days (7 Nights) Boston to Quebec City
Ship: Norwegian Gem
Departures: Sep 2024 to Oct 2025
Countries Visited: USA, Canada
Exclusive Solo Offer
INSIDE
$1,686
OCEANVIEW
$2,039
BALCONY
$3,645
SUITE
$3,722
From 1,686
View Trip
13 Day Eastern Seaboard Explorer with Viking Cruises
Cruise

13 Days (12 Nights) Montreal to New York
Cruise Line: Viking Cruises
Ships: Viking Mars, Viking Neptune
Departures: Sep 2024 to Sep 2026
Countries Visited: Canada, USA
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$9,895
SUITE
$16,825
Save 1,115
From 9,895
View Trip
Results: 18 results

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North American Cruises

USA Cruises Canada & New England Cruises Alaska Cruises Hawaii Cruises

Travel Styles

Luxury Cruises Short Cruise Breaks

Countries

Bahamas Bermuda Canada Iceland Mexico USA

Cities

Boston Los Angeles Montreal New York San Francisco Toronto Vancouver

Routes

Cruises from Baltimore to Baltimore Cruises from Boston to Montreal Cruises from Boston to Quebec City Cruises from Boston to Boston Cruises from Cape Liberty to Cape Liberty Cruises from Fort Lauderdale to Los Angeles Cruises from Fort Lauderdale to Fort Lauderdale Cruises from Fort Lauderdale to San Diego Cruises from Fort Lauderdale to Vancouver Cruises from Galveston to Galveston Cruises from Los Angeles to Miami Cruises from Los Angeles to Fort Lauderdale Cruises from Los Angeles to Vancouver Cruises from Los Angeles to Los Angeles Cruises from Miami to Los Angeles Cruises from Miami to Miami Cruises from Montreal to New York Cruises from New Orleans to New Orleans Cruises from New York to Montreal Cruises from New York to New York Cruises from New York to Quebec City Cruises from Orlando to Orlando Cruises from San Diego to Vancouver Cruises from San Diego to San Diego Cruises from San Francisco to San Francisco Cruises from Seattle to Seattle Cruises from Seward to Vancouver Cruises from Tampa to Tampa Cruises from Toronto to Vancouver Cruises from Vancouver to Vancouver Cruises from Vancouver to Los Angeles Cruises from Vancouver to San Diego

Country Routes

Cruises from Canada to USA Cruises from USA to Canada

Cruise Lines

Abercrombie & Kent APT Azamara Celebrity Cruises Celestyal Cruises Cunard Emerald Cruises Explora Journeys G Adventures Heritage Expeditions Holland America Hurtigruten Intrepid MSC Cruises Norwegian Cruise Line Oceania P&O Cruises P&O Cruises Worldwide Ponant Princess Regent Seven Seas Royal Caribbean Scenic Seabourn Silversea Tauck Travelmarvel Viking Virgin Voyages

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