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Cayman Islands Cruises

Are you looking for a cruise to Cayman Islands? Choose from 93 unique cruise itineraries to Cayman Islands, departing from Fort Lauderdale, Galveston, Los Angeles, Miami, New Orleans and more. February is the most popular month to cruise to Cayman Islands and we have over 301 departures available from ten of the world's leading cruise lines.
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93 Cruises (301 Cruise Departures)
10 Day Western Caribbean with Cunard
Cruise
 (9)

10 Days (9 Nights) Miami to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departures: Nov 2025 to Mar 2026
Countries Visited: USA, Cayman Islands, Jamaica, Honduras (+1 more), Mexico
INSIDE
$1,636
OCEANVIEW
$1,982
BALCONY
$2,576
SUITE
$6,239
From 1,636
View Trip
8 Day Western Caribbean with Holland America
Cruise
 (2)

8 Days (7 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Holland America
Ships: Nieuw Amsterdam, Nieuw Statendam
Departures: Dec 2024 to Dec 2024
Countries Visited: USA, Mexico, Cayman Islands, Jamaica (+1 more), Bahamas
Have It All Offer
INSIDE
$1,852
OCEANVIEW
$2,089
BALCONY
$2,466
SUITE
$3,238
From 1,852
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7 Day Western Caribbean Cruise with Royal Caribbean
Cruise
 (1)

7 Days (6 Nights) San Juan to Tampa
Cruise Line: Royal Caribbean
Ship: Rhapsody of the Seas
Departure: 02 November 2025
Countries Visited: Puerto Rico, Dominican Republic, Jamaica, Cayman Islands (+1 more), USA
Exclusive Deal
INSIDE
$1,106
OCEANVIEW
$1,345
BALCONY
$1,860
SUITE
$2,328
Save 453
From 1,007
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10 Day Aruba, Curacao & Bonaire with Celebrity Cruises
Cruise
 (2)

10 Days (9 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Eclipse
Departure: 05 December 2024
Countries Visited: USA, Bonaire, Aruba, Curacao (+1 more), Cayman Islands
Exclusive Deal
INSIDE
$1,518
OCEANVIEW
$1,905
BALCONY
$2,066
SUITE
$4,726
Save 2,659
From 1,422
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11 Day Western Caribbean Cruise with Royal Caribbean
Cruise

11 Days (10 Nights) Galveston to Galveston
Cruise Line: Royal Caribbean
Ship: Jewel of the Seas
Departure: 13 January 2025
Countries Visited: USA, Mexico, Belize, Honduras (+1 more), Cayman Islands
Exclusive Deal
INSIDE
$1,531
OCEANVIEW
$1,710
BALCONY
$2,142
SUITE
$4,594
Save 1,053
From 1,531
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16 Day Panama Canal Eastbound Cruise with Celebrity Cruises
Cruise

16 Days (15 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Summit
Departure: 19 September 2024
Countries Visited: USA, Mexico, Costa Rica, Colombia (+1 more), Cayman Islands
Exclusive Deal
INSIDE
$2,490
OCEANVIEW
$3,051
BALCONY
-
SUITE
-
Save 3,978
From 2,478
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8 Day Western Caribbean & Perfect Day with Royal Caribbean
Cruise

8 Days (7 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Royal Caribbean
Ship: Freedom of the Seas
Departures: Oct 2024 to Oct 2024
Countries Visited: USA, Bahamas, Haiti, Jamaica (+1 more), Cayman Islands
Exclusive Deal
INSIDE
$1,509
OCEANVIEW
$2,260
BALCONY
$2,379
SUITE
$3,715
Save 653
From 1,470
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10 Day Aruba, Bonaire & Curacao Cruise with Celebrity Cruises
Cruise

10 Days (9 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departure: 08 November 2024
Countries Visited: USA, Cayman Islands, Aruba, Curacao (+1 more), Bonaire
Exclusive Deal
INSIDE
$2,037
OCEANVIEW
$7,917
BALCONY
$3,373
SUITE
$27,690
Save 3,020
From 1,935
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8 Day Caribbean with Norwegian Cruise Line
Cruise

8 Days (7 Nights) Orlando to Orlando
Ship: Norwegian Jade
Departures: Jun 2024 to Aug 2024
Countries Visited: USA, Bahamas, Jamaica, Cayman Islands (+1 more), Mexico
INSIDE
$2,371
OCEANVIEW
$2,432
BALCONY
$3,327
SUITE
$3,503
From 2,371
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11 Day Western Caribbean Cruise with Royal Caribbean
Cruise

11 Days (10 Nights) Galveston to Galveston
Cruise Line: Royal Caribbean
Ship: Jewel of the Seas
Departure: 08 November 2024
Countries Visited: USA, Mexico, Belize, Honduras (+1 more), Cayman Islands
Exclusive Deal
INSIDE
$2,014
OCEANVIEW
$1,828
BALCONY
$2,746
SUITE
$3,379
Save 1,116
From 1,828
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10 Day Western Caribbean Cruise with Royal Caribbean
Cruise

10 Days (9 Nights) Tampa to Tampa
Cruise Line: Royal Caribbean
Ship: Enchantment of the Seas
Departure: 26 October 2024
Countries Visited: USA, Cayman Islands, Jamaica, Mexico (+1 more), Honduras
Exclusive Deal
INSIDE
$1,459
OCEANVIEW
$1,562
BALCONY
-
SUITE
$3,568
Save 546
From 1,311
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8 Day Western Caribbean & Perfect Day with Royal Caribbean
Cruise

8 Days (7 Nights) Miami to Miami
Cruise Line: Royal Caribbean
Ship: Independence of the Seas
Departure: 07 December 2025
Countries Visited: USA, Bahamas, Cayman Islands, Jamaica (+1 more), Haiti
Exclusive Deal
INSIDE
$1,716
OCEANVIEW
$2,086
BALCONY
$2,273
SUITE
$3,253
Save 619
From 1,501
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8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Seascape
Departures: Jun 2024 to Mar 2025
Countries Visited: USA, Jamaica, Cayman Islands, Mexico (+1 more), Bahamas
Mutiple Deals Available
INSIDE
$1,142
OCEANVIEW
$1,370
BALCONY
$1,678
SUITE
$2,331
From 1,142
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Seascape
Departure: 18 May 2024
Countries Visited: USA, Jamaica, Cayman Islands, Mexico (+1 more), Bahamas
All In Plus Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$2,202
SUITE
$3,479
From 2,202
View Trip
8 Day Western Caribbean with Holland America
Cruise

8 Days (7 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 17 November 2024
Countries Visited: USA, Mexico, Cayman Islands, Jamaica (+1 more), Bahamas
Have It All Offer
INSIDE
$1,961
OCEANVIEW
$2,159
BALCONY
$2,466
SUITE
$3,386
From 1,961
View Trip
11 Day Western Caribbean Cruise with Royal Caribbean
Cruise

11 Days (10 Nights) Galveston to Galveston
Cruise Line: Royal Caribbean
Ship: Jewel of the Seas
Departures: Dec 2024 to Apr 2025
Countries Visited: USA, Mexico, Belize, Honduras (+1 more), Cayman Islands
Exclusive Deal
INSIDE
$1,471
OCEANVIEW
$1,560
BALCONY
$1,972
SUITE
$3,171
Save 942
From 1,471
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11 Day A Journey From Miami To Miami with Explora Journeys
Cruise

11 Days (10 Nights) Miami to Miami
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 25 January 2026
Countries Visited: USA, Jamaica, Cayman Islands, Mexico (+1 more), Bahamas
Unique EscapesPenthouse Dream Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$7,168
SUITE
$8,752
From 7,168
View Trip
8 Day Caribbean with Norwegian Cruise Line
Cruise

8 Days (7 Nights) Orlando to Orlando
Ship: Norwegian Prima
Departures: Nov 2025 to Apr 2026
Countries Visited: USA, Bahamas, Jamaica, Cayman Islands (+1 more), Mexico
INSIDE
$2,157
OCEANVIEW
$2,540
BALCONY
$2,845
SUITE
$3,915
From 2,157
View Trip
8 Day Western Caribbean: Greater Antilles & Mexico with Holland America
Cruise

8 Days (7 Nights) Miami to Miami
Cruise Line: Holland America
Ship: Zuiderdam
Departures: Nov 2025 to Jan 2026
Countries Visited: USA, Bahamas, Jamaica, Cayman Islands (+1 more), Mexico
Have It All Offer
INSIDE
$1,911
OCEANVIEW
$2,159
BALCONY
$2,505
SUITE
$3,792
From 1,911
View Trip
13 Day Caribbean And Antilles with MSC Cruises
Cruise

13 Days (12 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Seascape
Departure: 05 April 2025
Countries Visited: USA, Bahamas, Jamaica, Cayman Islands (+1 more), Mexico
Early Booking Offer
INSIDE
$2,952
OCEANVIEW
$3,289
BALCONY
$3,695
SUITE
$4,675
From 2,952
View Trip
8 Day Western Caribbean Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) Miami to Miami
Cruise Line: Royal Caribbean
Ship: Independence of the Seas
Departure: 21 December 2025
Countries Visited: USA, Bahamas, Jamaica, Cayman Islands (+1 more), Mexico
Exclusive Deal
INSIDE
$2,341
OCEANVIEW
$3,127
BALCONY
$3,566
SUITE
$4,738
Save 856
From 2,044
View Trip
11 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

11 Days (10 Nights) Tampa to Tampa
Cruise Line: Royal Caribbean
Ships: Enchantment of the Seas, Grandeur of the Seas
Departures: Apr 2025 to Apr 2025
Countries Visited: USA, Cayman Islands, Aruba, Bonaire (+1 more), Curacao
Exclusive Deal
INSIDE
$1,805
OCEANVIEW
$2,003
BALCONY
$4,137
SUITE
$4,174
Save 704
From 1,576
View Trip
8 Day Western Caribbean - Port Canaveral with Norwegian Cruise Line
Cruise

8 Days (7 Nights) Orlando to Orlando
Ship: Norwegian Epic
Departures: Nov 2024 to Mar 2025
Countries Visited: USA, Mexico, Cayman Islands, Jamaica (+1 more), Bahamas
Exclusive Solo Offer
INSIDE
$2,075
OCEANVIEW
-
BALCONY
$2,839
SUITE
$3,114
From 2,075
View Trip
8 Day Western Caribbean - Port Canaveral with Norwegian Cruise Line
Cruise

8 Days (7 Nights) Orlando to Orlando
Ships: Norwegian Epic, Norwegian Prima
Departures: Feb 2025 to Feb 2026
Countries Visited: USA, Bahamas, Jamaica, Cayman Islands (+1 more), Mexico
INSIDE
$1,999
OCEANVIEW
$2,563
BALCONY
$2,868
SUITE
$3,452
From 1,999
View Trip
9 Day Caribbean And Antilles with MSC Cruises
Cruise

9 Days (8 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Seascape
Departure: 05 April 2025
Countries Visited: USA, Bahamas, Jamaica, Cayman Islands (+1 more), Mexico
Early Booking Offer
INSIDE
$2,127
OCEANVIEW
$2,365
BALCONY
$2,662
SUITE
$3,285
From 2,127
View Trip
12 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

12 Days (11 Nights) Galveston to Galveston
Cruise Line: Royal Caribbean
Ship: Jewel of the Seas
Departure: 18 November 2024
Countries Visited: USA, Mexico, Curacao, Aruba (+1 more), Cayman Islands
Exclusive Deal
INSIDE
$1,962
OCEANVIEW
$2,140
BALCONY
$2,594
SUITE
-
Save 743
From 1,664
View Trip
8 Day Western Caribbean with Holland America
Cruise

8 Days (7 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Holland America
Ships: Eurodam, Nieuw Amsterdam (+1 more), Nieuw Statendam
Departures: Nov 2024 to Mar 2026
Countries Visited: USA, Cayman Islands, Jamaica, Turks and Caicos Islands (+1 more), Bahamas
Have It All Offer
INSIDE
$1,763
OCEANVIEW
$2,149
BALCONY
$2,376
SUITE
$2,911
From 1,763
View Trip
8 Day Western Caribbean & Perfect Day with Royal Caribbean
Cruise

8 Days (7 Nights) Miami to Miami
Cruise Line: Royal Caribbean
Ship: Independence of the Seas
Departures: Nov 2025 to Apr 2026
Countries Visited: USA, Bahamas, Jamaica, Cayman Islands (+1 more), Mexico
Exclusive Deal
INSIDE
$1,503
OCEANVIEW
$1,858
BALCONY
$2,045
SUITE
$2,848
Save 760
From 1,341
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8 Day Western Caribbean with Princess
Cruise

8 Days (7 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Sky Princess
Departures: Dec 2024 to Feb 2025
Countries Visited: USA, Bahamas, Jamaica, Cayman Islands (+1 more), Mexico
INSIDE
$1,189
OCEANVIEW
$1,723
BALCONY
$1,447
SUITE
$1,814
From 1,189
View Trip
8 Day Season Of Sunshine with Regent Seven Seas
Cruise

8 Days (7 Nights) Miami to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Navigator
Departure: 06 December 2024
Countries Visited: USA, Mexico, Cayman Islands, Jamaica (+1 more), Bahamas
Exclusive Deal
INSIDE
-
OCEANVIEW
$5,770
BALCONY
$6,661
SUITE
$6,958
Save 2,950
From 5,770
View Trip
Results: 61-90 of 93

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