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Expedition Cruises Starting In September 2025

Are you looking to embark on an expedition cruise in September 2025? Choose from 71 unique cruise itineraries and 987 departures from the world's leading cruise lines.
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Departures (September 2025)
< August 2025 October 2025 >
Duration
6 Days
87 Days
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Price
$1,600pp
$124,495pp
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71 Cruises (987 Cruise Departures)
30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operated By: Cosmos
Departures: Sep 2024 to Nov 2025
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Savings
From 16,620
View Trip
10 Day Complete Galapagos (Grand Daphne) with Intrepid Travel
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: May 2024 to Dec 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 218
From 10,045
View Trip
10 Day Ultimate Galapagos: Central Islands (Grand Daphne) with Intrepid Travel
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jun 2024 to Dec 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save 1,597
From 8,653
View Trip
26 Day Ultimate South America with a Galapagos Cruise with Cosmos
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operated By: Cosmos
Departures: Sep 2024 to Nov 2025
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Savings
From 14,462
View Trip
9 Day Iberian Shores with Ponant
Cruise
 (2)

9 Days (8 Nights) Lisbon to Barcelona
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 24 September 2025
Countries Visited: Portugal, Spain
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$6,568
SUITE
$12,311
Save 122
From 6,568
View Trip
9 Day Cruising Southern Spain and Portugal - with Smithsonian Journeys with Ponant
Cruise
 (2)

9 Days (8 Nights) Barcelona to Lisbon
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 16 September 2025
Countries Visited: Spain, Portugal
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$9,439
SUITE
$15,917
Save 181
From 9,439
View Trip
17 Day Absolute Galapagos (Grand Daphne) with Intrepid Travel
Cruise

17 Days (16 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Sep 2024 to Dec 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 395
From 18,486
View Trip
12 Day Treasures of the Mediterranean Isles - Southbound with Tauck
Cruise

12 Days (11 Nights) Marseille to Valletta
Operated By: Tauck
Departures: May 2025 to Sep 2025
Trip Styles: Group, Cruise
Countries Visited: France, Italy, Corsica, Sardinia (+2 more), Sicily, Malta
From 17,390
View Trip
10 Day Galapagos - Central, West & East Islands aboard the Archipel I with Explore!
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: Explore!
Departures: Jun 2024 to Dec 2025
Trip Styles: Small Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 252
From 11,054
View Trip
17 Day Complete Galápagos - Eden with G Adventures
Cruise

17 Days (16 Nights) Quito to Quito
Operated By: G Adventures
Departures: Jun 2024 to Dec 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Deal
Save 3,186
From 11,721
View Trip
8 Day Galápagos - West & Central Islands aboard the Reina Silvia Voyager (Cruise Only) with G Adventures
Cruise

8 Days (7 Nights) Baltra Island to Baltra Island
Operated By: G Adventures
Departures: May 2024 to Dec 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Deal
Save 2,446
From 7,053
View Trip
29 Day Ultimate South America with Santiago Stopover & Galapagos Cruise with Cosmos
Tour + Cruise

29 Days Santiago to Guayaquil
Operated By: Cosmos
Departures: Sep 2024 to Nov 2025
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Chile, Brazil, Argentina, Peru (+2 more), Ecuador, Galapagos
Exclusive Savings
From 16,041
View Trip
12 Day Cruising the Great Lakes: Chicago to Toronto with Tauck
Cruise

12 Days (11 Nights) Chicago to Toronto
Operated By: Tauck
Departures: Aug 2024 to Sep 2025
Trip Styles: Group, Cruise
Countries Visited: USA, Canada
From 16,350
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departures: Jun 2024 to Mar 2026
Countries Visited: Ecuador, Galapagos
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
$15,642
SUITE
$18,513
From 15,642
View Trip
12 Day Sicily, the Amalfi Coast & Rome - Northbound with Tauck
Cruise

12 Days (11 Nights) Valletta to Rome
Operated By: Tauck
Departures: May 2025 to Oct 2025
Trip Styles: Group, Cruise
Countries Visited: Malta, Sicily, Italy
From 18,940
View Trip
18 Day Crossing the Equator: Portugal to Brazil with Scenic
Cruise

18 Days (17 Nights) Lisbon to Rio de Janeiro
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 24 September 2025
Countries Visited: Portugal, Spain, Cape Verde, Brazil
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$9,633
SUITE
$15,553
Save 13,097
From 9,633
View Trip
21 Day Transarctic, the Quest for the Two North Poles with Ponant
Cruise

21 Days (20 Nights) Paris to Seattle
Cruise Line: Ponant
Ship: Le Commandant-Charcot
Departure: 05 September 2025
Countries Visited: France, Norway, Arctic, USA
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$67,207
SUITE
$71,597
Save 1,340
From 67,207
View Trip
10 Day Galápagos - Central, South & East Islands aboard the Yolita with G Adventures
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: G Adventures
Departures: May 2024 to Jun 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive DealLast Minute Offer
Save 3,946
From 5,773
View Trip
15 Day Peru & the Galapagos Islands with Tauck
Tour + Cruise

15 Days Lima to Guayaquil
Operated By: Tauck
Departures: May 2024 to Oct 2025
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
From 21,350
View Trip
12 Day Canadian Remote Arctic: Northwest Passage to Ellesmere and Axel Heiberg Islands with Intrepid Travel
Cruise

12 Days (11 Nights) Calgary to Calgary
Operated By: Intrepid Travel
Departures: Aug 2024 to Sep 2025
Trip Styles: Group, Cruise
Countries Visited: Canada
Exclusive Savings
Save 648
From 29,478
View Trip
24 Day Darwin to Lautoka with Silversea
Cruise

24 Days (23 Nights) Darwin to Lautoka
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 06 September 2025
Countries Visited: Australia, Indonesia, Papua New Guinea, Solomon Islands (+2 more), Vanuatu, Fiji
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$37,719
BALCONY
$41,085
SUITE
$84,249
From 37,719
View Trip
15 Day Canada & East Coast Explorer with Viking Cruises
Cruise

15 Days (14 Nights) Toronto to Fort Lauderdale
Cruise Line: Viking Cruises
Ships: Viking Octantis, Viking Polaris
Departures: Oct 2024 to Sep 2025
Countries Visited: Canada, USA
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$13,855
SUITE
$19,300
Save 1,140
From 13,855
View Trip
27 Day Canada & the Northwest Passage with Viking Cruises
Cruise

27 Days (26 Nights) Nuuk to Toronto
Cruise Line: Viking Cruises
Ships: Viking Octantis, Viking Polaris
Departures: Sep 2025 to Sep 2026
Countries Visited: Greenland, Canada
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$41,575
SUITE
$65,038
Save 2,428
From 41,575
View Trip
7 Day Galápagos - North & Central Islands aboard the Eden with G Adventures
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: G Adventures
Departures: May 2024 to Dec 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Deal
Save 1,260
From 4,561
View Trip
12 Day Sicily, the Amalfi Coast & Rome - Southbound with Tauck
Cruise

12 Days (11 Nights) Rome to Valletta
Operated By: Tauck
Departures: Jun 2025 to Oct 2025
Trip Styles: Group, Cruise
Countries Visited: Italy, Sicily, Malta
From 18,170
View Trip
10 Day Venice & the Dalmatian Coast with Tauck
Cruise

10 Days (9 Nights) Venice to Venice
Operated By: Tauck
Departures: Sep 2024 to Sep 2025
Trip Styles: Group, Cruise, Island Hopping
Countries Visited: Italy, Croatia, Montenegro
From 15,990
View Trip
7 Day Galápagos - South & East Islands aboard the Yolita with G Adventures
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: G Adventures
Departures: May 2024 to Jun 2025
Trip Styles: Group, Cruise, Wildlife
Countries Visited: Ecuador
Exclusive DealLast Minute Offer
Save 2,793
From 4,086
View Trip
87 Day From the Arctic to Antarctica with Viking Cruises
Cruise

87 Days (86 Nights) Nuuk to Buenos Aires
Cruise Line: Viking Cruises
Ship: Viking Octantis
Departure: 03 September 2025
Countries Visited: Greenland, Canada, USA, Mexico (+8 more), Panama, Ecuador, Peru, Chile, Argentina, Antarctica, South Georgia Island, Falkland Islands
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$108,400
SUITE
$157,900
Save 3,095
From 108,400
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departures: Apr 2025 to Feb 2026
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$17,919
SUITE
$26,334
From 17,919
View Trip
12 Day Italy Cruise: Hidden Treasures from Florence to Venice with Abercrombie & Kent
New ReleaseCruise

12 Days (11 Nights) Florence to Venice
Operated By: Abercrombie & Kent
Departures: Sep 2024 to Sep 2025
Trip Styles: Group, Cruise
Countries Visited: Italy, Corsica, Sardinia, Sicily
Exclusive DealExclusive Solo Offer
Save 1,540
From 24,485
View Trip
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