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South America Tours Starting In October 2025

If you're looking at joining a tour through South America in October 2025, we have 167 unique tours and small group adventures with 10,901 departures from the world's leading tour operators departing in October.
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Departures (October 2025)
< September 2025 November 2025 >
Duration
3 Days
65 Days
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Price
$500pp
$68,875pp
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167 Tours (10,901 Tour Departures)
19 Day Ultimate South America with Cosmos
Tour
 (13)

19 Days Rio de Janeiro to Lima
Operated By: Cosmos
Departures: Sep 2024 to Nov 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Peru
Exclusive Savings
From 7,789
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20 Day Brazil, Argentina & Chile Unveiled with Peru with Cosmos
Tour
 (2)

20 Days Rio de Janeiro to Lima
Operated By: Cosmos
Departures: Jun 2024 to Nov 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Chile, Peru
Exclusive Savings
From 8,081
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22 Day South American Odyssey with Peru with Globus
Tour
 (3)

22 Days Rio de Janeiro to Lima
Operated By: Globus
Departures: Sep 2024 to Oct 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Chile, Peru
Exclusive Savings
Save 242
From 13,417
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23 Day Ultimate South America with Brazil's Amazon with Cosmos
Tour
 (3)

23 Days Manaus to Lima
Operated By: Cosmos
Departures: Sep 2024 to Nov 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Peru
Exclusive Savings
From 9,973
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30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operated By: Cosmos
Departures: Sep 2024 to Nov 2025
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Savings
From 16,620
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8 Day Highlights of Peru with Trafalgar
Tour
 (2)

8 Days Lima to Lima
Operated By: Trafalgar
Departures: Jun 2024 to Dec 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Peru
Exclusive Deal
Save 760
From 4,706
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8 Day Peru Splendours with Globus
Tour
 (2)

8 Days Lima to Lima
Operated By: Globus
Departures: Jun 2024 to Dec 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Peru
Exclusive Savings
Save 89
From 4,716
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26 Day South American Odyssey with Brazil's Amazon & Peru with Globus
Tour
 (2)

26 Days Manaus to Lima
Operated By: Globus
Departures: Sep 2024 to Oct 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Chile, Peru
Exclusive Savings
Save 282
From 15,790
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21 Day Absolute Peru (Inca Trail) with G Adventures
Tour
 (1)

21 Days Lima to Lima
Operated By: G Adventures
Departures: May 2024 to Dec 2025
Trip Styles: Adventure, Small Group, Walking & Hiking, Inca Trail
Countries Visited: Peru
Exclusive Deal
Save 1,462
From 5,282
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14 Day Adventures in Patagonia with Explore!
Tour
 (1)

14 Days Buenos Aires to Buenos Aires
Operated By: Explore!
Departures: Oct 2024 to Dec 2025
Trip Styles: Adventure, Group
Countries Visited: Chile, Argentina
Getaway Sale
Save 378
From 9,202
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17 Day Adventures in Patagonia with Iguazu Extension with Explore!
Tour
 (1)

17 Days Buenos Aires to Buenos Aires
Operated By: Explore!
Departures: Oct 2024 to Dec 2025
Trip Styles: Adventure, Small Group
Countries Visited: Chile, Argentina
Exclusive Savings
Save 220
From 10,496
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18 Day Andes, Iguassu & Beyond with G Adventures
Tour
 (1)

18 Days Santiago to Rio de Janeiro
Operated By: G Adventures
Departures: May 2024 to Dec 2025
Trip Styles: Adventure, Small Group
Countries Visited: Argentina, Chile, Brazil
Exclusive Savings
Save 131
From 5,487
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24 Day Brazil, Argentina & Chile Unveiled with Peru and Brazil's Amazon with Cosmos
Tour
 (1)

24 Days Manaus to Lima
Operated By: Cosmos
Departures: Jun 2024 to Nov 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Chile, Peru
Exclusive Savings
From 10,239
View Trip
9 Day Ecuador: Amazon, Hot Springs & Volcanoes with G Adventures
Tour
 (1)

9 Days Quito to Quito
Operated By: G Adventures
Departures: May 2024 to Dec 2025
Trip Styles: Adventure, Small Group
Countries Visited: Ecuador
Exclusive Deal
Save 746
From 2,153
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9 Day Galápagos Island Hopping with Quito with G Adventures
Tour
 (1)

9 Days Quito to Quito
Operated By: G Adventures
Departures: May 2024 to Dec 2025
Trip Styles: Adventure, Group, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Deal
Save 903
From 3,326
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23 Day Grand South America with Luxury Gold
Tour
 (1)

23 Days Lima to Rio de Janeiro
Operated By: Luxury Gold
Departures: Sep 2024 to Nov 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Peru, Chile, Argentina, Brazil
Founder's Collection
Save 494
From 27,432
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9 Day Iguassu & Beyond with G Adventures
Tour
 (1)

9 Days Buenos Aires to Rio de Janeiro
Operated By: G Adventures
Departures: Jun 2024 to Dec 2025
Trip Styles: Adventure, Small Group
Countries Visited: Argentina, Brazil
Exclusive Deal
Save 665
From 2,534
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11 Day In the Footsteps of the Incas with Trafalgar
Tour
 (1)

11 Days Lima to Lima
Operated By: Trafalgar
Departures: Jun 2024 to Dec 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Peru
Exclusive Deal
Save 774
From 8,007
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12 Day South American Getaway with Santiago with Globus
Tour
 (1)

12 Days Rio de Janeiro to Santiago
Operated By: Globus
Departures: Jul 2024 to Dec 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Chile
Exclusive Savings
Save 125
From 6,826
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23 Day South American Odyssey with Brazil Amazon & Easter Island with Globus
Tour
 (1)

23 Days Manaus to Santiago
Operated By: Globus
Departures: Sep 2024 to Oct 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Easter Island, Chile
Exclusive Savings
Save 258
From 15,268
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6 Day Torres del Paine - The W Trek with G Adventures
Tour
 (1)

6 Days Puerto Natales to Puerto Natales
Operated By: G Adventures
Departures: Oct 2024 to Mar 2026
Trip Styles: Adventure, Small Group, Short Break, Walking & Hiking
Countries Visited: Chile
Exclusive Deal
Save 305
From 2,494
View Trip
26 Day Ultimate South America with a Galapagos Cruise with Cosmos
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operated By: Cosmos
Departures: Sep 2024 to Nov 2025
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Savings
From 14,462
View Trip
11 Day Wild Peru with Crooked Compass
New ReleaseTour
 (1)

11 Days Cusco to Cusco
Operated By: Crooked Compass
Departures: Oct 2024 to Oct 2025
Trip Styles: Adventure, Small Group, Walking & Hiking, Cultural, Off The Beaten Track
Countries Visited: Peru
From 8,060
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6 Day Peru & the Amazon: Cusco to Lima with G Adventures
New ReleaseTour

6 Days Cusco to Lima
Operated By: G Adventures
Departures: Aug 2024 to Nov 2025
Trip Styles: Adventure, Small Group, Short Break, Wildlife, Cultural, Scenic
Countries Visited: Peru
Exclusive Deal
Save 436
From 3,563
View Trip
19 Day South American Odyssey with Easter Island with Globus
Tour

19 Days Rio de Janeiro to Santiago
Operated By: Globus
Departures: Sep 2024 to Mar 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Chile, Easter Island
Exclusive Savings
Save 218
From 12,896
View Trip
9 Day Impressions of South America with Trafalgar
Tour

9 Days Rio de Janeiro to Buenos Aires
Operated By: Trafalgar
Departures: May 2024 to Dec 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina
Exclusive Deal
Save 696
From 6,496
View Trip
30 Day The Scenic Route with G Adventures
Tour

30 Days Lima to Buenos Aires
Operated By: G Adventures
Departures: May 2024 to Dec 2025
Trip Styles: Adventure, Small Group
Countries Visited: Argentina, Chile, Bolivia, Peru
Exclusive Savings
Save 198
From 8,819
View Trip
4 Day Trekking the Inca Trail (Inca Trail) with G Adventures
Tour

4 Days Cusco to Cusco
Operated By: G Adventures
Departures: May 2024 to Jan 2026
Trip Styles: Adventure, Small Group, Camping, Short Break, Walking & Hiking, Inca Trail
Countries Visited: Peru
Exclusive Savings
Save 31
From 1,195
View Trip
13 Day The Best of Brazil and Argentina with Brazil's Amazon with Cosmos
Tour

13 Days Manaus to Buenos Aires
Operated By: Cosmos
Departures: Jun 2024 to Nov 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina
Exclusive Savings
Save 86
From 5,652
View Trip
3 Day Machu Picchu by Train Independent Adventure with G Adventures
Tour

3 Days Cusco to Cusco
Operated By: G Adventures
Departures: May 2024 to Dec 2025
Trip Styles: Adventure, Group, Rail, Short Break
Countries Visited: Peru
Exclusive Savings
Save 24
From 1,116
View Trip
Results: 1-30 of 167

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Cities

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