Mediterranean Luxury Cruises

Explore the best luxury cruises in the Mediterranean. Choose from 456 unique cruise itineraries from 10 leading cruise lines. May is the most popular month to join a luxury cruise in the Mediterranean with 544 departures starting between June 2024 and April 2027.
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5 Days
51 Days
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$1,200pp
$52,570pp
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456 Cruises (544 Cruise Departures)
Cruise

13 Days (12 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Departure: 04 October 2025
Countries Visited: Italy, Sicily, Malta, Greece (+1 more), Turkey
Exclusive Deal
INSIDE
$6,964
OCEANVIEW
$8,033
BALCONY
$9,251
SUITE
$12,419
Save 2,056
From 6,964
Cruise

22 Days (21 Nights) Barcelona to Barcelona
Cruise Line: Cunard
Departure: 04 May 2026
Countries Visited: Spain, Greece, Turkey, France (+1 more), Italy
Exclusive Deal
INSIDE
$3,521
OCEANVIEW
$3,867
BALCONY
$4,560
SUITE
$11,886
From 3,521
Cruise

8 Days (7 Nights) Rome to Istanbul
Cruise Line: Cunard
Departure: 12 May 2025
Countries Visited: Italy, Greece, Turkey
Exclusive Deal
INSIDE
$1,486
OCEANVIEW
$1,684
BALCONY
$1,833
SUITE
$4,258
From 1,486
Cruise

15 Days (14 Nights) Barcelona to Barcelona
Cruise Line: Cunard
Departure: 04 May 2026
Countries Visited: Spain, Greece, Turkey
Exclusive Deal
INSIDE
$2,578
OCEANVIEW
$3,023
BALCONY
$3,469
SUITE
$8,419
From 2,578
Cruise

29 Days (28 Nights) Rome to Barcelona
Cruise Line: Cunard
Departure: 15 September 2025
Countries Visited: Italy, Greece, Montenegro, Croatia (+3 more), Malta, Spain, Turkey
Exclusive Deal
INSIDE
$4,761
OCEANVIEW
$5,553
BALCONY
$6,196
SUITE
$16,146
From 4,761
Cruise

29 Days (28 Nights) Barcelona to Rome
Cruise Line: Cunard
Departure: 04 May 2026
Countries Visited: Spain, Greece, Turkey, France (+3 more), Italy, Corsica, Sicily
Exclusive Deal
INSIDE
$4,414
OCEANVIEW
$4,810
BALCONY
$5,602
SUITE
$14,859
From 4,414
Cruise

8 Days (7 Nights) Barcelona to Istanbul
Cruise Line: Cunard
Departure: 04 May 2026
Countries Visited: Spain, Greece, Turkey
Exclusive Deal
INSIDE
$1,585
OCEANVIEW
$1,783
BALCONY
$1,981
SUITE
$4,456
From 1,585
Cruise

8 Days (7 Nights) Barcelona to Istanbul
Cruise Line: Cunard
Departures: Sep 2024 to Sep 2025
Countries Visited: Spain, Greece, Turkey
Exclusive Deal
INSIDE
$1,486
OCEANVIEW
$1,684
BALCONY
$1,882
SUITE
$4,258
From 1,486
Cruise

15 Days (14 Nights) Rome to Rome
Cruise Line: Cunard
Departure: 21 September 2026
Countries Visited: Italy, Greece, Turkey
Exclusive Deal
INSIDE
$2,578
OCEANVIEW
$3,023
BALCONY
$3,469
SUITE
$8,419
From 2,578
Cruise

13 Days (12 Nights) Rome to Athens
Cruise Line: Regent Seven Seas
Departure: 28 September 2024
Countries Visited: Italy, Sicily, Malta, Greece (+2 more), Turkey, Cyprus
Explore More OfferExclusive Deal
INSIDE
-
OCEANVIEW
$7,422
BALCONY
-
SUITE
$18,339
Save 10,198
From 7,422
Cruise

29 Days (28 Nights) Barcelona to Rome
Cruise Line: Cunard
Departure: 07 September 2026
Countries Visited: Spain, Corsica, Sicily, Italy (+3 more), France, Greece, Turkey
Exclusive Deal
INSIDE
$4,909
OCEANVIEW
$5,305
BALCONY
$6,097
SUITE
$17,829
From 4,909
New ReleaseCruise

22 Days (21 Nights) Athens to Aqaba
Cruise Line: Emerald Cruises
Ship: Emerald Kaia
Departure: 21 October 2026
Countries Visited: Greece, Turkey, Cyprus, Israel (+2 more), Egypt, Jordan
Exclusive Deal
INSIDE
-
OCEANVIEW
$22,364
BALCONY
-
SUITE
$29,774
Save 8,226
From 22,364
Cruise

13 Days (12 Nights) Barcelona to Istanbul
Cruise Line: Oceania Cruises
Departure: 14 September 2025
Countries Visited: Spain, France, Italy, Sicily (+2 more), Greece, Turkey
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$7,827
SUITE
$12,371
Save 2,063
From 7,827
Cruise

24 Days (23 Nights) Rome to Athens
Cruise Line: Oceania Cruises
Departure: 04 October 2025
Countries Visited: Italy, Sicily, Malta, Greece (+2 more), Turkey, Cyprus
Exclusive Deal
INSIDE
$10,681
OCEANVIEW
$13,285
BALCONY
$15,116
SUITE
$20,977
Save 2,079
From 10,681
Cruise

23 Days (22 Nights) London to Rome
Cruise Line: Cunard
Departure: 04 May 2025
Countries Visited: England, Spain, Italy, Greece (+1 more), Turkey
Exclusive Deal
INSIDE
$3,373
OCEANVIEW
$4,115
BALCONY
$4,709
SUITE
$10,897
From 3,373
Cruise

22 Days (21 Nights) Athens to Dubrovnik
Cruise Line: Seabourn
Ship: Encore
Departure: 04 May 2025
Countries Visited: Greece, Cyprus, Turkey, Italy (+1 more), Croatia
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$17,945
SUITE
$31,746
From 17,945
Cruise

16 Days (15 Nights) London to Istanbul
Cruise Line: Cunard
Departure: 04 May 2025
Countries Visited: England, Spain, Italy, Greece (+1 more), Turkey
Exclusive Deal
INSIDE
$2,628
OCEANVIEW
$2,974
BALCONY
$3,964
SUITE
$7,429
From 2,628
Cruise

18 Days (17 Nights) Monte Carlo to Istanbul
Cruise Line: Regent Seven Seas
Departure: 20 April 2025
Countries Visited: Monaco, Italy, Turkey, Greece
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$17,087
SUITE
$19,305
Save 11,203
From 17,087
Cruise

15 Days (14 Nights) Athens to Rome
Cruise Line: Emerald Cruises
Departure: 19 July 2025
Countries Visited: Greece, Turkey, Italy, Sicily
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$43,134
Save 9,436
From 43,134
Cruise

15 Days (14 Nights) Rome to Istanbul
Cruise Line: Cunard
Departure: 14 September 2026
Countries Visited: Italy, France, Greece, Turkey
Exclusive Deal
INSIDE
$3,023
OCEANVIEW
$3,419
BALCONY
$3,865
SUITE
$9,409
From 3,023
Cruise

15 Days (14 Nights) Barcelona to Istanbul
Cruise Line: Regent Seven Seas
Departure: 22 October 2024
Countries Visited: Spain, Italy, Sicily, Malta (+4 more), Croatia, Montenegro, Greece, Turkey
Explore More OfferExclusive Deal
INSIDE
-
OCEANVIEW
$8,672
BALCONY
$10,421
SUITE
$12,320
Save 13,128
From 8,672
Cruise

15 Days (14 Nights) Rome to Athens
Cruise Line: Emerald Cruises
Departure: 07 June 2025
Countries Visited: Italy, Sicily, Greece, Turkey
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$16,345
Save 6,165
From 16,345
Cruise

11 Days (10 Nights) Valletta to Antalya
Cruise Line: Ponant
Ship: L'Austral
Departure: 07 May 2025
Countries Visited: Malta, Sicily, Italy, Greece (+1 more), Turkey
Exclusive Savings
INSIDE
-
OCEANVIEW
$11,912
BALCONY
$12,569
SUITE
$23,711
Save 228
From 11,912
Cruise

15 Days (14 Nights) Barcelona to Istanbul
Cruise Line: Regent Seven Seas
Departure: 02 April 2025
Countries Visited: Spain, Malta, Greece, Egypt (+2 more), Cyprus, Turkey
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$15,826
SUITE
$17,460
Save 6,944
From 15,826
Cruise

15 Days (14 Nights) Barcelona to Barcelona
Cruise Line: Cunard
Departure: 30 September 2024
Countries Visited: Spain, Greece, Turkey, Sicily
Exclusive Deal
INSIDE
$3,221
OCEANVIEW
$3,568
BALCONY
-
SUITE
$7,924
From 3,221
Cruise

17 Days (16 Nights) Barcelona to Athens
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 19 June 2024
Countries Visited: Spain, Sicily, Malta, Greece (+1 more), Turkey
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
$14,008
SUITE
$16,236
From 14,008
Cruise

10 Days (9 Nights) Rome to Athens
Cruise Line: Silversea
Ship: Silver Muse
Departure: 26 November 2025
Countries Visited: Italy, Sicily, Malta, Greece
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$7,920
BALCONY
$10,296
SUITE
$18,513
From 7,920
Cruise

22 Days (21 Nights) Rome to Rome
Cruise Line: Cunard
Departure: 14 September 2026
Countries Visited: Italy, France, Greece, Turkey
Exclusive Deal
INSIDE
$4,016
OCEANVIEW
$4,362
BALCONY
$5,055
SUITE
$13,173
From 4,016
Cruise

10 Days (9 Nights) Barcelona to Athens
Cruise Line: Oceania Cruises
Departure: 26 May 2025
Countries Visited: Spain, Malta, Greece, Turkey
Cabin Upgrade Offer
INSIDE
$4,537
OCEANVIEW
$5,606
BALCONY
$5,606
SUITE
$7,131
From 4,537
Cruise
 (2)

21 Days (20 Nights) Rome to Lisbon
Cruise Line: Oceania Cruises
Departure: 18 October 2025
Countries Visited: Italy, Sicily, Malta, Tunisia (+5 more), Monaco, France, Spain, Portugal, Morocco
Exclusive Deal
INSIDE
$8,578
OCEANVIEW
$9,647
BALCONY
$13,924
SUITE
$18,993
Save 2,062
From 8,578
Results: 391-420 of 456

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