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Mediterranean Luxury Cruises

Explore the best luxury cruises in the Mediterranean. Choose from 456 unique cruise itineraries from 10 leading cruise lines. May is the most popular month to join a luxury cruise in the Mediterranean with 544 departures starting between June 2024 and April 2027.
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456 Cruises (544 Cruise Departures)
8 Day France And Italy with Cunard
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 16 June 2025
Countries Visited: Spain, France, Sardinia, Sicily (+1 more), Italy
Exclusive Deal
INSIDE
$1,387
OCEANVIEW
$1,635
BALCONY
$1,833
SUITE
$4,159
From 1,387
View Trip
11 Day Flair, Flavor & Culture with Regent Seven Seas
Cruise

11 Days (10 Nights) Monte Carlo to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 20 April 2025
Countries Visited: Monaco, Italy, Turkey, Greece
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$9,545
SUITE
$11,396
Save 7,685
From 9,545
View Trip
8 Day A Journey From Barcelona To Rome with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 13 May 2025
Countries Visited: Spain, France, Corsica, Sardinia (+1 more), Italy
Unique Escapes
INSIDE
-
OCEANVIEW
-
BALCONY
$6,192
SUITE
$7,529
From 6,192
View Trip
8 Day A Journey From Barcelona To Civitavecchia with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 16 June 2025
Countries Visited: Spain, France, Corsica, Italy (+1 more), Sardinia
Unique EscapesPenthouse Dream Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$5,846
SUITE
$7,108
From 5,846
View Trip
8 Day Italy, France And Spain with Cunard
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 20 July 2026
Countries Visited: Italy, France, Corsica, Spain
Exclusive Deal
INSIDE
$1,585
OCEANVIEW
$1,783
BALCONY
$1,932
SUITE
$4,654
From 1,585
View Trip
12 Day Lisbon to Rome with Silversea
Cruise

12 Days (11 Nights) Lisbon to Rome
Cruise Line: Silversea
Ship: Silver Spirit
Departure: 04 October 2024
Countries Visited: France, Italy, Monaco, Portugal (+1 more), Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$12,078
BALCONY
$13,959
SUITE
$12,870
From 12,078
View Trip
8 Day Iberian Illumination with Oceania Cruises
Cruise

8 Days (7 Nights) Lisbon to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 01 May 2025
Countries Visited: Portugal, Spain, Morocco, France
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$5,684
SUITE
$7,506
Save 2,046
From 5,684
View Trip
8 Day Alluring Rivieras: Cote d'Azur & Italian Coastline with Scenic
Cruise

8 Days (7 Nights) Monte Carlo to Rome
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 06 May 2025
Countries Visited: France, Italy, Monaco
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$11,103
SUITE
$14,117
Save 2,612
From 11,103
View Trip
13 Day Mediterranean Melody with Oceania Cruises
Cruise

13 Days (12 Nights) Barcelona to Athens
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 15 September 2025
Countries Visited: Spain, France, Monaco, Italy (+3 more), Sicily, Greece, Turkey
Exclusive Deal
INSIDE
$6,926
OCEANVIEW
-
BALCONY
$9,371
SUITE
$12,539
Save 2,054
From 6,926
View Trip
11 Day Islands of the Mediterranean: Spain to Malta with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Barcelona to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 25 April 2026
Countries Visited: Spain, Corsica, Sardinia, Sicily (+1 more), Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
$10,489
BALCONY
-
SUITE
$14,449
Save 2,606
From 10,489
View Trip
7 Day Rome to Monte Carlo with Silversea
Cruise

7 Days (6 Nights) Rome to Monte Carlo
Cruise Line: Silversea
Ship: Silver Ray
Departure: 30 May 2025
Countries Visited: Italy, Monaco
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$9,999
From 9,999
View Trip
10 Day Spanish Shores & Beyond with Emerald Cruises
New ReleaseCruise

10 Days (9 Nights) Barcelona to Palma de Mallorca
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 10 September 2026
Countries Visited: Spain, France, Monaco, Corsica (+1 more), Sardinia
Exclusive Deal
INSIDE
-
OCEANVIEW
$10,143
BALCONY
-
SUITE
$13,657
Save 2,102
From 10,143
View Trip
8 Day Western Mediterranean with Cunard
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 01 September 2025
Countries Visited: Italy, France, Spain
Exclusive Deal
INSIDE
$1,486
OCEANVIEW
$1,734
BALCONY
$1,932
SUITE
$4,258
From 1,486
View Trip
21 Day Discover the Yachting Treasures of the Mediterranean with Emerald Cruises
New ReleaseCruise

21 Days (20 Nights) Santa Cruz de Tenerife to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 15 April 2026
Countries Visited: Spain, Morocco, Corsica, Sardinia (+2 more), Sicily, Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
$19,246
BALCONY
-
SUITE
$26,918
Save 6,694
From 19,246
View Trip
8 Day A Journey From Barcelona To Civitavecchia with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 08 September 2025
Countries Visited: Spain, France, Italy, Corsica (+1 more), Sardinia
Unique Escapes
INSIDE
-
OCEANVIEW
-
BALCONY
$5,846
SUITE
$7,108
From 5,846
View Trip
10 Day Nice to Valletta with Silversea
Cruise

10 Days (9 Nights) Nice to Valletta
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 07 September 2025
Countries Visited: France, Italy, Sardinia, Sicily (+1 more), Malta
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$12,177
BALCONY
$14,553
SUITE
$20,790
From 12,177
View Trip
13 Day Dawn Of Civilization with Oceania Cruises
Cruise

13 Days (12 Nights) Rome to Athens
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 30 October 2024
Countries Visited: Italy, France, Malta, Sicily (+3 more), Croatia, Montenegro, Greece
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$8,557
SUITE
$12,488
Save 2,073
From 8,557
View Trip
8 Day Italy, France And Spain with Cunard
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 07 September 2026
Countries Visited: Spain, Corsica, Sicily, Italy
Exclusive Deal
INSIDE
$1,536
OCEANVIEW
$1,684
BALCONY
$1,783
SUITE
$4,258
From 1,536
View Trip
18 Day Andalusian Nights & Barcelona Open with Seabourn
Cruise

18 Days (17 Nights) Rome to Lisbon
Cruise Line: Seabourn
Ship: Venture
Departure: 13 April 2025
Countries Visited: Italy, France, Spain, Morocco (+1 more), Portugal
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$16,935
SUITE
$40,918
From 16,935
View Trip
11 Day Tyrrhenian Treasures & Malta with Seabourn
Cruise

11 Days (10 Nights) Monte Carlo to Barcelona
Cruise Line: Seabourn
Ship: Ovation
Departure: 21 August 2024
Countries Visited: Monaco, France, Italy, Sicily (+3 more), Malta, Corsica, Spain
More Moments On Us Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$11,096
SUITE
$18,224
From 11,096
View Trip
11 Day Andalusian Nights: Spotlight On Seville with Seabourn
Cruise

11 Days (10 Nights) Barcelona to Lisbon
Cruise Line: Seabourn
Ship: Venture
Departure: 20 April 2025
Countries Visited: Spain, France, Morocco, Portugal
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$11,036
SUITE
$26,941
From 11,036
View Trip
11 Day Classical Greece & Italy with Oceania Cruises
Cruise

11 Days (10 Nights) Athens to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 20 October 2024
Countries Visited: Greece, Croatia, Montenegro, Malta (+2 more), Sicily, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$7,566
SUITE
$10,258
Save 2,064
From 7,566
View Trip
7 Day Icons of the French Riviera and Portofino with Scenic
New ReleaseCruise

7 Days (6 Nights) Barcelona to Nice
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 15 May 2026
Countries Visited: Spain, France, Italy, Monaco
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$8,410
SUITE
$13,370
Save 3,085
From 8,410
View Trip
31 Day Mediterranean Jewels, Spain & Morocco with Seabourn
Cruise

31 Days (30 Nights) Rome to Rome
Cruise Line: Seabourn
Ship: Ovation
Departure: 15 May 2025
Countries Visited: Italy, Malta, Tunisia, France (+6 more), Spain, Gibraltar, Morocco, Monaco, Corsica, Sardinia
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$25,609
SUITE
$67,011
From 25,609
View Trip
11 Day Pearls of Southern Spain & Portugal with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Lisbon to Barcelona
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 08 October 2026
Countries Visited: Portugal, Spain, Morocco
Exclusive Deal
INSIDE
-
OCEANVIEW
$11,182
BALCONY
-
SUITE
$15,142
Save 2,613
From 11,182
View Trip
8 Day A Journey From Barcelona To Civitavecchia with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departures: Jul 2025 to Aug 2025
Countries Visited: French Southern and Antarctic Lands, France, Corsica, Sardinia (+1 more), Italy
Unique EscapesPenthouse Dream Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$5,940
SUITE
$7,247
From 5,940
View Trip
11 Day Flavors Of The Mediterranean with Regent Seven Seas
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Navigator
Departure: 18 September 2024
Countries Visited: Spain, France, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
$10,802
BALCONY
-
SUITE
$17,306
Save 5,248
From 10,802
View Trip
15 Day Italy, France And Spain with Cunard
Cruise

15 Days (14 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 09 June 2025
Countries Visited: Italy, Corsica, Spain, France (+2 more), Sardinia, Sicily
Exclusive Deal
INSIDE
$2,528
OCEANVIEW
$2,776
BALCONY
$3,221
SUITE
$7,825
From 2,528
View Trip
16 Day Split to Lisbon with Silversea
Cruise

16 Days (15 Nights) Split to Lisbon
Cruise Line: Silversea
Ship: Silver Dawn
Departure: 12 May 2026
Countries Visited: Croatia, Gibraltar, Italy, Portugal (+4 more), Spain, Tunisia, Malta, Montenegro
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$16,533
BALCONY
$18,810
SUITE
$36,927
From 16,533
View Trip
8 Day French & Italian Rivieras with Corsica with Emerald Cruises
Cruise

8 Days (7 Nights) Nice to Rome
Cruise Line: Emerald Cruises
Ships: Emerald Sakara
Departures: Oct 2024 to Jun 2026
Countries Visited: France, Italy, Corsica, Monaco
Exclusive Deal
INSIDE
-
OCEANVIEW
$6,876
BALCONY
-
SUITE
$9,130
Save 1,581
From 6,876
View Trip
Results: 181-210 of 456

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