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Cruises from USA to Spain

Are you looking for a cruise from USA to Spain? April is the most popular month to cruise between USA and Spain and there are 33 departures available from eleven of the world's leading cruise lines.
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13 Days
84 Days
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32 Cruises (33 Cruise Departures)
14 Day Atlantic Ocean Passage with Viking Cruises
Cruise
 (4)

14 Days (13 Nights) Fort Lauderdale to Barcelona
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Mar 2025 to Feb 2026
Countries Visited: USA, Sint Maarten, Portugal, Spain
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$4,945
SUITE
$8,905
Save 1,066
From 4,945
View Trip
15 Day Cultural Crossing With Madeira And Morocco with Holland America
Cruise
 (1)

15 Days (14 Nights) Fort Lauderdale to Barcelona
Cruise Line: Holland America
Ship: Oosterdam
Departure: 19 April 2025
Countries Visited: USA, Bermuda, Portugal, Morocco (+1 more), Spain
Have It All Offer
INSIDE
$2,730
OCEANVIEW
$3,027
BALCONY
$3,473
SUITE
$6,789
From 2,730
View Trip
32 Day Fire, Ice & Greenland Grand Adventure with Princess
Cruise
 (2)

32 Days (31 Nights) New York to Barcelona
Cruise Line: Princess
Ship: Island Princess
Departure: 05 July 2024
Countries Visited: USA, Canada, Greenland, Iceland (+5 more), Scotland, England, Spain, Portugal, Morocco
INSIDE
$7,942
OCEANVIEW
$8,170
BALCONY
$10,318
SUITE
$12,265
From 7,942
View Trip
25 Day Transatlantic Tranquility with Oceania Cruises
Cruise
 (2)

25 Days (24 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 12 April 2025
Countries Visited: USA, Curacao, Aruba, Grenada (+9 more), Barbados, Guadeloupe, Saint Kitts and Nevis, Puerto Rico, Saint Barthelemy, Antigua and Barbuda, Portugal, Morocco, Spain
Exclusive Deal
INSIDE
$9,254
OCEANVIEW
$10,165
BALCONY
$13,065
SUITE
$16,956
Save 2,066
From 9,254
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15 Day Spanish Passage with Princess
Cruise
 (3)

15 Days (14 Nights) Fort Lauderdale to Barcelona
Cruise Line: Princess
Ship: Majestic Princess
Departure: 18 February 2025
Countries Visited: USA, Portugal, Spain
INSIDE
$1,186
OCEANVIEW
-
BALCONY
$1,514
SUITE
$2,651
From 1,186
View Trip
17 Day A Journey From Miami To Barcelona with Explora Journeys
Cruise

17 Days (16 Nights) Miami to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 02 April 2025
Countries Visited: USA, Bermuda, Portugal, Spain
The Total Luxury Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$9,148
SUITE
$11,157
From 9,148
View Trip
39 Day A Grand Journey From Latin Shores To European Enclaves with Explora Journeys
Cruise

39 Days (38 Nights) Los Angeles to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 12 May 2024
Countries Visited: USA, Mexico, Guatemala, Costa Rica (+6 more), Panama, Colombia, Saint Barthelemy, Antigua and Barbuda, Spain, Morocco
The Total Luxury Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$23,849
From 23,849
View Trip
15 Day Bermuda & Spain Transatlantic with Celebrity Cruises
Cruise

15 Days (14 Nights) Orlando to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 19 April 2025
Countries Visited: USA, Bermuda, Portugal, Spain
Exclusive Offer
INSIDE
$1,653
OCEANVIEW
$1,846
BALCONY
$2,444
SUITE
$8,442
Save 2,779
From 1,653
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29 Day Splendor Across The Seas with Regent Seven Seas
Cruise

29 Days (28 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 13 March 2026
Countries Visited: USA, Bermuda, Portugal, Spain (+3 more), Morocco, Italy, France
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$26,485
SUITE
$30,475
Save 11,835
From 26,485
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84 Day Grand Arctic Adventure with Regent Seven Seas
Cruise

84 Days (83 Nights) New York to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 10 July 2025
Countries Visited: USA, Canada, Greenland, Iceland (+18 more), Faroe Islands, Scotland, Northern Ireland, Ireland, Wales, England, France, Belgium, Holland, Denmark, Germany, Poland, Lithuania, Latvia, Sweden, Norway, Spain, Portugal
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$96,144
SUITE
$106,044
Save 29,326
From 96,144
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21 Day MSC Grand Voyages with MSC Cruises
Cruise

21 Days (20 Nights) Miami to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 08 November 2024
Countries Visited: USA, Virgin Islands, Antigua and Barbuda, Sint Maarten (+4 more), Martinique, Barbados, Portugal, Spain
Early Booking Offer
INSIDE
-
OCEANVIEW
$2,722
BALCONY
$3,365
SUITE
$7,196
From 2,722
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise

19 Days (18 Nights) Miami to Alicante
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 08 November 2024
Countries Visited: USA, Virgin Islands, Antigua and Barbuda, Sint Maarten (+4 more), Martinique, Barbados, Portugal, Spain
Early Booking Offer
INSIDE
$2,123
OCEANVIEW
$2,420
BALCONY
$2,985
SUITE
$6,004
From 2,123
View Trip
13 Day Spain & Azores Transatlantic with Royal Caribbean
Cruise

13 Days (12 Nights) Miami to Barcelona
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 30 April 2025
Countries Visited: USA, Portugal, Spain
Exclusive Deal
INSIDE
$1,476
OCEANVIEW
$1,789
BALCONY
$2,228
SUITE
$3,436
Save 801
From 1,476
View Trip
16 Day Miami to Casablanca & Barcelona with Virgin Voyages
Cruise

16 Days (15 Nights) Miami to Barcelona
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 03 May 2025
Countries Visited: USA, Spain, Morocco
INSIDE
$2,971
OCEANVIEW
$3,084
BALCONY
$3,379
SUITE
$8,563
From 2,971
View Trip
15 Day Bermuda & Iberia with Oceania Cruises
Cruise

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 07 April 2026
Countries Visited: USA, Bermuda, Portugal, Gibraltar (+1 more), Spain
Exclusive Deal
INSIDE
$4,839
OCEANVIEW
$5,987
BALCONY
$6,829
SUITE
$9,403
Save 2,031
From 4,839
View Trip
14 Day Bermuda & Portugal Transatlantic with Celebrity Cruises
Cruise

14 Days (13 Nights) Fort Lauderdale to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Apex
Departure: 08 March 2025
Countries Visited: USA, Bermuda, Portugal, Spain
Exclusive Offer
INSIDE
$1,781
OCEANVIEW
$1,878
BALCONY
$2,548
SUITE
$7,655
Save 2,778
From 1,781
View Trip
84 Day Grand Arctic Adventure with Regent Seven Seas
Cruise

84 Days (83 Nights) New York to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 02 June 2024
Countries Visited: USA, Canada, Greenland, Iceland (+18 more), Faroe Islands, Scotland, Ireland, England, Wales, France, Belgium, Holland, Denmark, Sweden, Germany, Poland, Lithuania, Finland, Estonia, Norway, Spain, Portugal
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$98,071
SUITE
$107,674
Save 18,589
From 98,071
View Trip
24 Day MSC Grand Voyages with MSC Cruises
Cruise

24 Days (23 Nights) Miami to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaside
Departure: 06 April 2025
Countries Visited: USA, Sint Maarten, Antigua and Barbuda, Barbados (+5 more), Portugal, Spain, Sicily, Italy, France
Early Booking Offer
INSIDE
$3,289
OCEANVIEW
$3,834
BALCONY
$4,467
SUITE
$6,339
From 3,289
View Trip
14 Day Spain & Canary Crossing with Royal Caribbean
Cruise

14 Days (13 Nights) Miami to Barcelona
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 28 April 2024
Countries Visited: USA, Spain
Exclusive Deal
INSIDE
$2,468
OCEANVIEW
-
BALCONY
$3,885
SUITE
-
Save 883
From 1,999
View Trip
15 Day Spanish Passage with Princess
Cruise

15 Days (14 Nights) Fort Lauderdale to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departure: 22 March 2025
Countries Visited: USA, Spain
INSIDE
$1,879
OCEANVIEW
$2,572
BALCONY
$3,424
SUITE
$4,255
From 1,879
View Trip
17 Day Transatlantic Cruise with Royal Caribbean
Cruise

17 Days (16 Nights) Galveston to Barcelona
Cruise Line: Royal Caribbean
Ship: Harmony of the Seas
Departure: 16 March 2026
Countries Visited: USA, Bahamas, Spain
Exclusive Deal
INSIDE
$2,729
OCEANVIEW
$3,289
BALCONY
$3,271
SUITE
-
Save 1,016
From 2,404
View Trip
15 Day Atlantic Isle Exploration with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 07 April 2026
Countries Visited: USA, Bermuda, Portugal, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$11,104
SUITE
$12,648
Save 7,046
From 11,104
View Trip
15 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise

15 Days (14 Nights) New York to Barcelona
Ship: Norwegian Sky
Departure: 21 October 2024
Countries Visited: USA, Canada, Portugal, Spain
Free At Sea Offer
INSIDE
$2,887
OCEANVIEW
$3,114
BALCONY
$4,480
SUITE
$8,856
From 2,887
View Trip
16 Day Azores & Spain Transatlantic with Royal Caribbean
Cruise

16 Days (15 Nights) Galveston to Barcelona
Cruise Line: Royal Caribbean
Ship: Voyager of the Seas
Departure: 01 May 2024
Countries Visited: USA, Bahamas, Portugal, Spain
Exclusive Deal
INSIDE
$2,499
OCEANVIEW
$3,182
BALCONY
$4,428
SUITE
-
Save 1,435
From 2,499
View Trip
45 Day A Grand Journey Connecting Continents with Explora Journeys
Cruise

45 Days (44 Nights) Vancouver to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 06 May 2024
Countries Visited: Canada, USA, Mexico, Guatemala (+7 more), Costa Rica, Panama, Colombia, Saint Barthelemy, Antigua and Barbuda, Morocco, Spain
The Total Luxury Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$28,156
From 28,156
View Trip
20 Day A Transatlantic Journey From Miami To Moroccan Fantasies with Explora Journeys
Cruise

20 Days (19 Nights) Miami to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 31 May 2024
Countries Visited: USA, Saint Barthelemy, Antigua and Barbuda, Spain (+1 more), Morocco
Exclusive DealThe Total Luxury Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$10,583
SUITE
$12,291
From 10,583
View Trip
14 Day Spain & Azores Transatlantic with Royal Caribbean
Cruise

14 Days (13 Nights) Orlando to Barcelona
Cruise Line: Royal Caribbean
Ship: Voyager of the Seas
Departure: 03 May 2025
Countries Visited: USA, Portugal, Spain
Exclusive Deal
INSIDE
$1,788
OCEANVIEW
$2,103
BALCONY
$3,068
SUITE
$4,894
Save 693
From 1,578
View Trip
13 Day A Journey From Miami To Lanzarote with Explora Journeys
Cruise

13 Days (12 Nights) Miami to Arrecife
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 31 May 2024
Countries Visited: USA, Saint Barthelemy, Antigua and Barbuda, Spain
Exclusive DealThe Total Luxury Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$5,341
SUITE
$6,207
From 5,341
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise

17 Days (16 Nights) Miami to Valencia
Cruise Line: MSC Cruises
Ship: MSC Seaside
Departure: 06 April 2025
Countries Visited: USA, Sint Maarten, Antigua and Barbuda, Barbados (+2 more), Portugal, Spain
Early Booking Offer
INSIDE
$2,370
OCEANVIEW
$2,676
BALCONY
$3,112
SUITE
$4,785
From 2,370
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise

20 Days (19 Nights) Miami to Valencia
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 08 November 2024
Countries Visited: USA, Virgin Islands, Antigua and Barbuda, Sint Maarten (+4 more), Martinique, Barbados, Portugal, Spain
Early Booking Offer
INSIDE
$2,294
OCEANVIEW
$2,591
BALCONY
$2,927
SUITE
$5,462
From 2,294
View Trip
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