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South America Tours Starting In October 2025

If you're looking at joining a tour through South America in October 2025, we have 172 unique tours and small group adventures with 11,279 departures from the world's leading tour operators departing in October.
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Departures (October 2025)
< September 2025 November 2025 >
Duration
3 Days
65 Days
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Price
$500pp
$68,875pp
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172 Tours (11,279 Tour Departures)
19 Day Ultimate South America with Cosmos
Tour
 (13)

19 Days Rio de Janeiro to Lima
Operated By: Cosmos
Departures: Sep 2024 to Nov 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Peru
Exclusive Savings
From 7,789
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20 Day Brazil, Argentina & Chile Unveiled with Peru with Cosmos
Tour
 (2)

20 Days Rio de Janeiro to Lima
Operated By: Cosmos
Departures: Jun 2024 to Nov 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Chile, Peru
Exclusive Savings
From 8,081
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22 Day South American Odyssey with Peru with Globus
Tour
 (3)

22 Days Rio de Janeiro to Lima
Operated By: Globus
Departures: Sep 2024 to Oct 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Chile, Peru
Exclusive Savings
Save 242
From 13,417
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23 Day Ultimate South America with Brazil's Amazon with Cosmos
Tour
 (3)

23 Days Manaus to Lima
Operated By: Cosmos
Departures: Sep 2024 to Nov 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Peru
Exclusive Savings
From 9,973
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30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operated By: Cosmos
Departures: Sep 2024 to Nov 2025
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Savings
From 16,620
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8 Day Highlights of Peru with Trafalgar
Tour
 (2)

8 Days Lima to Lima
Operated By: Trafalgar
Departures: Jun 2024 to Dec 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Peru
Exclusive Deal
Save 760
From 4,706
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8 Day Peru Splendours with Globus
Tour
 (2)

8 Days Lima to Lima
Operated By: Globus
Departures: Jun 2024 to Dec 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Peru
Exclusive Savings
Save 89
From 4,716
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26 Day South American Odyssey with Brazil's Amazon & Peru with Globus
Tour
 (2)

26 Days Manaus to Lima
Operated By: Globus
Departures: Sep 2024 to Oct 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Chile, Peru
Exclusive Savings
Save 282
From 15,790
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21 Day Absolute Peru (Inca Trail) with G Adventures
Tour
 (1)

21 Days Lima to Lima
Operated By: G Adventures
Departures: May 2024 to Dec 2025
Trip Styles: Adventure, Small Group, Walking & Hiking, Inca Trail
Countries Visited: Peru
Exclusive Deal
Save 1,462
From 5,282
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14 Day Adventures in Patagonia with Explore!
Tour
 (1)

14 Days Buenos Aires to Buenos Aires
Operated By: Explore!
Departures: Oct 2024 to Dec 2025
Trip Styles: Adventure, Group
Countries Visited: Chile, Argentina
Asia Sale
Save 378
From 9,202
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17 Day Adventures in Patagonia with Iguazu Extension with Explore!
Tour
 (1)

17 Days Buenos Aires to Buenos Aires
Operated By: Explore!
Departures: Oct 2024 to Dec 2025
Trip Styles: Adventure, Small Group
Countries Visited: Chile, Argentina
Exclusive Savings
Save 220
From 10,496
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18 Day Andes, Iguassu & Beyond with G Adventures
Tour
 (1)

18 Days Santiago to Rio de Janeiro
Operated By: G Adventures
Departures: May 2024 to Dec 2025
Trip Styles: Adventure, Small Group
Countries Visited: Argentina, Chile, Brazil
Exclusive Savings
Save 131
From 5,487
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24 Day Brazil, Argentina & Chile Unveiled with Peru and Brazil's Amazon with Cosmos
Tour
 (1)

24 Days Manaus to Lima
Operated By: Cosmos
Departures: Jun 2024 to Nov 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Chile, Peru
Exclusive Savings
From 10,239
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14 Day Discover Patagonia with G Adventures
Tour
 (1)

14 Days Buenos Aires to Buenos Aires
Operated By: G Adventures
Departures: Oct 2024 to Dec 2025
Trip Styles: Adventure, Small Group
Countries Visited: Argentina, Chile
Exclusive Deal
Save 926
From 7,573
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9 Day Ecuador: Amazon, Hot Springs & Volcanoes with G Adventures
Tour
 (1)

9 Days Quito to Quito
Operated By: G Adventures
Departures: May 2024 to Dec 2025
Trip Styles: Adventure, Small Group
Countries Visited: Ecuador
Exclusive Deal
Save 746
From 2,153
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9 Day Galápagos Island Hopping with Quito with G Adventures
Tour
 (1)

9 Days Quito to Quito
Operated By: G Adventures
Departures: May 2024 to Dec 2025
Trip Styles: Adventure, Group, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Deal
Save 903
From 3,326
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23 Day Grand South America with Luxury Gold
Tour
 (1)

23 Days Lima to Rio de Janeiro
Operated By: Luxury Gold
Departures: Sep 2024 to Nov 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Peru, Chile, Argentina, Brazil
Founder's Collection
Save 494
From 27,432
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9 Day Iguassu & Beyond with G Adventures
Tour
 (1)

9 Days Buenos Aires to Rio de Janeiro
Operated By: G Adventures
Departures: Jun 2024 to Dec 2025
Trip Styles: Adventure, Small Group
Countries Visited: Argentina, Brazil
Exclusive Deal
Save 665
From 2,534
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11 Day In the Footsteps of the Incas with Trafalgar
Tour
 (1)

11 Days Lima to Lima
Operated By: Trafalgar
Departures: Jun 2024 to Dec 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Peru
Exclusive Deal
Save 774
From 8,007
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12 Day South American Getaway with Santiago with Globus
Tour
 (1)

12 Days Rio de Janeiro to Santiago
Operated By: Globus
Departures: Jul 2024 to Dec 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Chile
Exclusive Savings
Save 125
From 6,826
View Trip
23 Day South American Odyssey with Brazil Amazon & Easter Island with Globus
Tour
 (1)

23 Days Manaus to Santiago
Operated By: Globus
Departures: Sep 2024 to Oct 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Easter Island, Chile
Exclusive Savings
Save 258
From 15,268
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6 Day Torres del Paine - The W Trek with G Adventures
Tour
 (1)

6 Days Puerto Natales to Puerto Natales
Operated By: G Adventures
Departures: Oct 2024 to Apr 2026
Trip Styles: Adventure, Small Group, Short Break, Walking & Hiking
Countries Visited: Chile
Exclusive Deal
Save 305
From 2,494
View Trip
26 Day Ultimate South America with a Galapagos Cruise with Cosmos
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operated By: Cosmos
Departures: Sep 2024 to Nov 2025
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Savings
From 14,462
View Trip
11 Day Wild Peru with Crooked Compass
New ReleaseTour
 (1)

11 Days Cusco to Cusco
Operated By: Crooked Compass
Departures: Oct 2024 to Oct 2025
Trip Styles: Adventure, Small Group, Walking & Hiking, Cultural, Off The Beaten Track
Countries Visited: Peru
From 8,060
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31 Day Bolivia to Brazil: Highlands & Coastlines with G Adventures
Tour

31 Days La Paz to Rio de Janeiro
Operated By: G Adventures
Departures: May 2024 to Dec 2025
Trip Styles: Adventure, Small Group, 18-30's
Countries Visited: Argentina, Brazil, Chile, Bolivia (+1 more), Uruguay
Exclusive Deal
Save 1,497
From 5,702
View Trip
12 Day Wonders of the Galápagos & Machu Picchu: Eastern Islands Route with Abercrombie & Kent
New ReleaseTour + Cruise

12 Days Guayaquil to Lima
Operated By: Abercrombie & Kent
Departures: Apr 2025 to Oct 2025
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Ecuador, Galapagos, Peru
From 27,245
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14 Day End of the Earth with G Adventures
Tour

14 Days Buenos Aires to Buenos Aires
Operated By: G Adventures
Departures: Oct 2024 to Mar 2026
Trip Styles: Adventure, Small Group
Countries Visited: Argentina, Chile
Exclusive Savings
Save 154
From 6,075
View Trip
22 Day Colombian Culture, Caribbean & Lost City with G Adventures
Tour

22 Days Bogota to Santa Marta
Operated By: G Adventures
Departures: May 2024 to Dec 2025
Trip Styles: Adventure, Small Group
Countries Visited: Colombia
Exclusive Deal
Save 1,316
From 5,013
View Trip
26 Day Ultimate South America with a Santiago Stopover, Arequipa & the Colca Canyon with Cosmos
Tour

26 Days Santiago to Lima
Operated By: Cosmos
Departures: Sep 2024 to Nov 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Chile, Brazil, Argentina, Peru
Exclusive Savings
From 10,831
View Trip
7 Day Peru Explorer with Costsaver
Tour

7 Days Lima to Cusco
Operated By: Costsaver
Departures: May 2024 to Dec 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Peru
Exclusive Deal
Save 230
From 2,188
View Trip
Results: 1-30 of 172

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Cities

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Routes

Tours from Bogota to Cartagena Tours from Buenos Aires to Buenos Aires Tours from Buenos Aires to Rio de Janeiro Tours from Cusco to Cusco Tours from Lima to Rio de Janeiro Tours from Lima to Lima Tours from Lima to Cusco Tours from Lima to La Paz Tours from Quito to Quito Tours from Rio de Janeiro to Lima Tours from Santiago to Buenos Aires Tours from Santiago to Santiago

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