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Mediterranean Luxury Cruises

Explore the best luxury cruises in the Mediterranean. Choose from 457 unique cruise itineraries from 10 leading cruise lines. September is the most popular month to join a luxury cruise in the Mediterranean with 550 departures starting between May 2024 and April 2027.
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457 Cruises (550 Cruise Departures)
11 Day Malta, Italian Shores and Isle of Beauty with Ponant
Cruise
 (1)

11 Days (10 Nights) Nice to Valletta
Cruise Line: Ponant
Ship: Le Bougainville
Departures: Aug 2024 to Aug 2024
Countries Visited: France, Corsica, Italy, Malta
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$9,168
SUITE
$15,675
Save 462
From 9,168
View Trip
10 Day Cities Of The Western Med Voyage with Azamara Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 31 October 2024
Countries Visited: Italy, Monaco, France, Spain
Circle Club Voyage
INSIDE
-
OCEANVIEW
-
BALCONY
$4,219
SUITE
$5,512
From 4,219
View Trip
11 Day Renaissance Triumphs with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Riviera
Departure: 04 November 2024
Countries Visited: Italy, Sicily, Malta, France (+1 more), Spain
Exclusive DealSingles Special Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$6,398
SUITE
$9,091
Save 2,052
From 6,398
View Trip
11 Day Malta, Italian Shores and Isle of Beauty with Ponant
Cruise
 (1)

11 Days (10 Nights) Valletta to Nice
Cruise Line: Ponant
Ship: Le Bougainville
Departures: Jul 2024 to Aug 2024
Countries Visited: Malta, Italy, Corsica, France
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$10,168
SUITE
$21,183
Save 202
From 10,168
View Trip
22 Day Discover the Wonders of the Mediterranean with Emerald Cruises
New ReleaseCruise
 (1)

22 Days (21 Nights) Athens to Lisbon
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 17 October 2026
Countries Visited: Greece, Sicily, Malta, Italy (+4 more), Corsica, Spain, Morocco, Portugal
Exclusive Deal
INSIDE
-
OCEANVIEW
$21,523
BALCONY
-
SUITE
$29,641
Save 6,717
From 21,523
View Trip
12 Day Mediterranean Springtime in France and Italy with Ponant
Cruise
 (1)

12 Days (11 Nights) Nice to Nice
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 10 May 2025
Countries Visited: France, Italy, Sicily, Sardinia (+1 more), Corsica
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$11,296
SUITE
$21,302
Save 214
From 11,296
View Trip
12 Day Spain Intensive Voyage with Azamara Cruises
Cruise
 (1)

12 Days (11 Nights) Barcelona to Lisbon
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 06 November 2025
Countries Visited: Spain, Gibraltar, Portugal
INSIDE
$4,625
OCEANVIEW
$5,087
BALCONY
$5,777
SUITE
$7,500
From 4,625
View Trip
11 Day Mediterranean Delights with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Monte Carlo to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 27 June 2025
Countries Visited: Monaco, France, Spain, Sardinia (+3 more), Tunisia, Sicily, Italy
Exclusive Deal
INSIDE
$5,360
OCEANVIEW
$5,815
BALCONY
$8,261
SUITE
$11,102
Save 2,040
From 5,360
View Trip
11 Day Autumnal Mediterranean with Oceania Cruises
Cruise
 (2)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 18 October 2025
Countries Visited: Italy, Sicily, Malta, Tunisia (+3 more), Monaco, France, Spain
Exclusive Deal
INSIDE
$4,726
OCEANVIEW
$5,181
BALCONY
$7,626
SUITE
$10,309
Save 2,034
From 4,726
View Trip
13 Day Eternal Classics with Oceania Cruises
Cruise
 (1)

13 Days (12 Nights) Rome to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Riviera
Departure: 13 August 2024
Countries Visited: Italy, Sicily, Malta, Greece
Exclusive DealSingles Special Offer
INSIDE
$7,073
OCEANVIEW
$8,370
BALCONY
$9,360
SUITE
$12,835
Save 2,057
From 7,073
View Trip
11 Day Mediterranean Awakening with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Monte Carlo
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 17 June 2025
Countries Visited: Spain, France, Corsica, Italy (+1 more), Monaco
Exclusive Deal
INSIDE
$5,578
OCEANVIEW
$6,043
BALCONY
$8,479
SUITE
$11,171
Save 2,042
From 5,578
View Trip
8 Day France And Italy with Cunard
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 04 August 2025
Countries Visited: Italy, France, Sardinia, Sicily
INSIDE
$1,427
OCEANVIEW
$1,645
BALCONY
$1,873
SUITE
$3,833
From 1,427
View Trip
6 Day Grand Prix Weekend Voyage with Azamara Cruises
Cruise

6 Days (5 Nights) Barcelona to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Pursuit
Departure: 23 May 2024
Countries Visited: Spain, France
INSIDE
$2,539
OCEANVIEW
$2,317
BALCONY
-
SUITE
-
From 2,317
View Trip
21 Day France, Italy & Maltese Gems with Seabourn
Cruise

21 Days (20 Nights) Barcelona to Barcelona
Cruise Line: Seabourn
Ship: Ovation
Departures: May 2025 to Oct 2025
Countries Visited: Spain, France, Italy, Corsica (+3 more), Sardinia, Malta, Tunisia
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$15,839
SUITE
$28,714
From 15,839
View Trip
8 Day Italy, France And Spain with Cunard
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 07 September 2026
Countries Visited: Spain, Corsica, Sicily, Italy
INSIDE
$1,635
OCEANVIEW
$1,783
BALCONY
$1,932
SUITE
$4,258
From 1,635
View Trip
21 Day Tyrrhenian Treasures & Mediterranean Jewels with Seabourn
Cruise

21 Days (20 Nights) Monte Carlo to Monte Carlo
Cruise Line: Seabourn
Ship: Ovation
Departure: 30 August 2025
Countries Visited: Monaco, Italy, Sicily, Malta (+4 more), Corsica, France, Spain, Sardinia
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$16,512
SUITE
$28,882
From 16,512
View Trip
18 Day Discover the Ancient Treasures of the Mediterranean & Red Sea with Emerald Cruises
New ReleaseCruise

18 Days (17 Nights) Cairo to Athens
Cruise Line: Emerald Cruises
Ship: Emerald Kaia
Departure: 07 April 2027
Countries Visited: Egypt, Jordan, Israel, Cyprus (+2 more), Turkey, Greece
Exclusive Deal
INSIDE
-
OCEANVIEW
$18,355
BALCONY
-
SUITE
$24,220
Save 6,685
From 18,355
View Trip
15 Day Italy, France And Spain with Cunard
Cruise

15 Days (14 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departures: Aug 2024 to Sep 2025
Countries Visited: Italy, France, Spain, Sardinia (+2 more), Corsica, Sicily
INSIDE
$2,766
OCEANVIEW
$3,033
BALCONY
$3,568
SUITE
$7,399
From 2,766
View Trip
9 Day Rome to Barcelona with Silversea
Cruise

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Spirit
Departure: 10 November 2025
Countries Visited: Italy, France, Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$8,118
BALCONY
$9,306
SUITE
$9,009
From 8,118
View Trip
9 Day Springtime Rivieras with Oceania Cruises
Cruise

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 18 May 2025
Countries Visited: Italy, Corsica, France, Spain
Cabin Upgrade Offer
INSIDE
$4,734
OCEANVIEW
$5,417
BALCONY
$6,338
SUITE
$7,021
From 4,734
View Trip
13 Day Mediterranean Melody with Oceania Cruises
Cruise

13 Days (12 Nights) Barcelona to Athens
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 15 September 2025
Countries Visited: Spain, France, Monaco, Italy (+3 more), Sicily, Greece, Turkey
Exclusive Deal
INSIDE
$6,926
OCEANVIEW
-
BALCONY
$9,371
SUITE
$12,539
Save 2,054
From 6,926
View Trip
12 Day Sicily, the Amalfi Coast & Rome - Southbound with Tauck
Cruise

12 Days (11 Nights) Rome to Valletta
Operated By: Tauck
Departures: Jun 2025 to Oct 2025
Trip Styles: Group, Cruise
Countries Visited: Italy, Sicily, Malta
From 18,170
View Trip
9 Day Flavors Of Luxury with Regent Seven Seas
Cruise

9 Days (8 Nights) Valletta to Monte Carlo
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 14 September 2024
Countries Visited: Malta, Spain, France, Corsica (+1 more), Monaco
Explore More OfferExclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$7,190
SUITE
$7,732
Save 9,000
From 7,190
View Trip
12 Day Lisbon to Rome with Silversea
Cruise

12 Days (11 Nights) Lisbon to Rome
Cruise Line: Silversea
Ship: Silver Spirit
Departure: 04 October 2024
Countries Visited: France, Italy, Monaco, Portugal (+1 more), Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$12,078
BALCONY
$14,652
SUITE
$12,870
From 12,078
View Trip
8 Day A Journey Of Limoncello Days And Catalonia Nights with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 02 September 2024
Countries Visited: Italy, Sicily, Tunisia, Spain
Exclusive DealUnique Escapes
INSIDE
-
OCEANVIEW
-
BALCONY
$5,613
SUITE
$6,826
From 5,613
View Trip
21 Day Mediterranean Overture & Rivieras with Seabourn
Cruise

21 Days (20 Nights) Barcelona to Barcelona
Cruise Line: Seabourn
Ship: Ovation
Departure: 31 July 2025
Countries Visited: Spain, France, Monaco, Italy (+4 more), Corsica, Sardinia, Malta, Tunisia
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$15,165
SUITE
$28,545
From 15,165
View Trip
12 Day Rome to Barcelona with Silversea
Cruise

12 Days (11 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 07 May 2025
Countries Visited: Italy, Monaco, France, Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$14,256
From 14,256
View Trip
15 Day Italy, France And Spain with Cunard
Cruise

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 04 August 2025
Countries Visited: Italy, France, Sardinia, Sicily (+2 more), Corsica, Spain
INSIDE
$2,677
OCEANVIEW
$3,033
BALCONY
$3,568
SUITE
$7,399
From 2,677
View Trip
20 Day Mediterranean And Greek Islands with Cunard
Cruise

20 Days (19 Nights) London to London
Cruise Line: Cunard
Ship: Queen Anne
Departure: 07 September 2025
Countries Visited: England, Spain, Greece, Turkey (+1 more), Sicily
INSIDE
$2,946
OCEANVIEW
$4,243
BALCONY
$5,787
SUITE
$15,054
From 2,946
View Trip
31 Day Jewels Of Spain, Italy & France with Seabourn
Cruise

31 Days (30 Nights) Barcelona to Rome
Cruise Line: Seabourn
Ship: Ovation
Departure: 15 April 2025
Countries Visited: Spain, Sardinia, France, Italy (+4 more), Monaco, Sicily, Malta, Corsica
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$24,432
SUITE
-
From 24,432
View Trip
Results: 31-60 of 457

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