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Mediterranean Luxury Cruises

Explore the best luxury cruises in the Mediterranean. Choose from 457 unique cruise itineraries from 10 leading cruise lines. September is the most popular month to join a luxury cruise in the Mediterranean with 550 departures starting between May 2024 and April 2027.
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457 Cruises (550 Cruise Departures)
10 Day Rome to Nice with Silversea
Cruise

10 Days (9 Nights) Rome to Nice
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 18 May 2024
Countries Visited: France, Italy
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$13,068
BALCONY
$15,642
SUITE
-
From 13,068
View Trip
15 Day Italy, France And Spain with Cunard
Cruise

15 Days (14 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 08 July 2024
Countries Visited: Italy, France, Spain, Sardinia (+2 more), Corsica, Sicily
INSIDE
$2,974
OCEANVIEW
$3,192
BALCONY
$3,677
SUITE
$8,320
From 2,974
View Trip
8 Day Italian & Aegean Sampler with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Athens
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 13 October 2024
Countries Visited: Italy, Greece
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$13,176
Save 2,124
From 13,176
View Trip
10 Day Monte Carlo to Barcelona with Silversea
Cruise

10 Days (9 Nights) Monte Carlo to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 29 July 2025
Countries Visited: Monaco, France, Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$10,593
From 10,593
View Trip
8 Day Enchanting Italian Coastlines with Emerald Cruises
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departures: Aug 2025 to Aug 2026
Countries Visited: Italy, Sardinia, Corsica
Exclusive Deal
INSIDE
-
OCEANVIEW
$7,272
BALCONY
-
SUITE
$9,583
Save 1,577
From 7,272
View Trip
10 Day Barcelona to Monte Carlo with Silversea
Cruise

10 Days (9 Nights) Barcelona to Monte Carlo
Cruise Line: Silversea
Ship: Silver Ray
Departure: 29 August 2025
Countries Visited: Spain, France, Monaco
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$10,593
From 10,593
View Trip
15 Day Italy, France And Spain with Cunard
Cruise

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 13 July 2026
Countries Visited: Italy, France, Corsica, Spain
INSIDE
$3,172
OCEANVIEW
$3,518
BALCONY
$3,964
SUITE
$8,518
From 3,172
View Trip
15 Day Italy, France And Spain with Cunard
Cruise

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 07 September 2026
Countries Visited: Spain, Corsica, Sicily, Italy (+1 more), France
INSIDE
$2,974
OCEANVIEW
$3,320
BALCONY
$3,766
SUITE
$7,924
From 2,974
View Trip
8 Day Italy And Spain with Cunard
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 17 August 2026
Countries Visited: Spain, Sardinia, Sicily, Italy
INSIDE
$1,684
OCEANVIEW
$1,882
BALCONY
$2,080
SUITE
$4,654
From 1,684
View Trip
18 Day Discover the Ancient Treasures of the Mediterranean & Red Sea with Emerald Cruises
New ReleaseCruise

18 Days (17 Nights) Cairo to Athens
Cruise Line: Emerald Cruises
Ship: Emerald Kaia
Departure: 07 April 2027
Countries Visited: Egypt, Jordan, Israel, Cyprus (+2 more), Turkey, Greece
Exclusive Deal
INSIDE
-
OCEANVIEW
$18,355
BALCONY
-
SUITE
$24,220
Save 6,685
From 18,355
View Trip
12 Day Golden Coasts of Italy and France with Emerald Cruises
New ReleaseCruise

12 Days (11 Nights) Nice to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 26 May 2026
Countries Visited: France, Monaco, Italy, Corsica (+1 more), Sardinia
Exclusive Deal
INSIDE
-
OCEANVIEW
$11,430
BALCONY
-
SUITE
$15,588
Save 3,115
From 11,430
View Trip
15 Day Discover the Splendours of Italian & French coastlines with Emerald Cruises
New ReleaseCruise

15 Days (14 Nights) Nice to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 27 June 2026
Countries Visited: France, Monaco, Italy, Corsica (+1 more), Sardinia
Exclusive Deal
INSIDE
-
OCEANVIEW
$13,405
BALCONY
-
SUITE
$18,652
Save 5,135
From 13,405
View Trip
12 Day Rome to Barcelona with Silversea
Cruise

12 Days (11 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 07 May 2025
Countries Visited: Italy, Monaco, France, Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$14,256
From 14,256
View Trip
13 Day Tyrrhenian Treasures & Malta with Seabourn
Cruise

13 Days (12 Nights) Monte Carlo to Rome
Cruise Line: Seabourn
Ship: Ovation
Departure: 10 September 2024
Countries Visited: Monaco, Italy, Sicily, Malta (+3 more), Corsica, France, Spain
More Moments On Us Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$13,375
SUITE
$22,087
From 13,375
View Trip
8 Day French Riviera & the Catalan Coastline with Scenic
Cruise

8 Days (7 Nights) Nice to Barcelona
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 27 May 2025
Countries Visited: France, Corsica, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$10,509
SUITE
$14,563
Save 2,606
From 10,509
View Trip
21 Day France & Spanish Treasures with Seabourn
Cruise

21 Days (20 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Ovation
Departures: Jul 2024 to Jun 2025
Countries Visited: Italy, Malta, Tunisia, France (+3 more), Spain, Gibraltar, Morocco
The Sail Away EventMore Moments On Us Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$14,571
SUITE
$30,312
From 14,571
View Trip
12 Day Mediterranean Mosaic with Regent Seven Seas
Cruise

12 Days (11 Nights) Monte Carlo to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 21 June 2025
Countries Visited: Monaco, France, Spain, Tunisia (+2 more), Malta, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$14,349
SUITE
$15,904
Save 6,631
From 14,349
View Trip
15 Day Athens to Lisbon with Silversea
Cruise

15 Days (14 Nights) Athens to Lisbon
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 14 November 2025
Countries Visited: Greece, Italy, Malta, Tunisia (+2 more), Spain, Portugal
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$12,078
BALCONY
$12,969
SUITE
$20,889
From 12,078
View Trip
10 Day Valletta to Nice with Silversea
Cruise

10 Days (9 Nights) Valletta to Nice
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 18 July 2025
Countries Visited: Malta, Sicily, Sardinia, Italy (+1 more), France
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$11,880
BALCONY
$14,454
SUITE
$20,790
From 11,880
View Trip
12 Day Cultures of the Mediterranean with Emerald Cruises
New ReleaseCruise

12 Days (11 Nights) Rome to Barcelona
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 29 October 2024
Countries Visited: Italy, Sicily, Malta, Tunisia (+2 more), Sardinia, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$12,568
Save 2,627
From 12,568
View Trip
10 Day Spanish Shores & Beyond with Emerald Cruises
New ReleaseCruise

10 Days (9 Nights) Palma de Mallorca to Barcelona
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 19 September 2026
Countries Visited: Spain, Sardinia, Corsica, Monaco (+1 more), France
Exclusive Deal
INSIDE
-
OCEANVIEW
$10,143
BALCONY
-
SUITE
$13,657
Save 2,102
From 10,143
View Trip
11 Day A Journey From Athens To Barcelona with Explora Journeys
Cruise

11 Days (10 Nights) Athens to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 31 October 2024
Countries Visited: Greece, Malta, Italy, France (+1 more), Spain
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
$5,881
SUITE
$7,187
From 5,881
View Trip
9 Day Rome to Rome with Silversea
Cruise

9 Days (8 Nights) Rome to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 15 September 2025
Countries Visited: Italy, Sicily, Tunisia, France
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$12,078
From 12,078
View Trip
9 Day Springtime Rivieras with Oceania Cruises
Cruise

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 18 May 2025
Countries Visited: Italy, Corsica, France, Spain
Cabin Upgrade Offer
INSIDE
$4,734
OCEANVIEW
$5,417
BALCONY
$6,338
SUITE
$7,021
From 4,734
View Trip
21 Day Spain, Morocco & Mediterranean Overture with Seabourn
Cruise

21 Days (20 Nights) Barcelona to Rome
Cruise Line: Seabourn
Ship: Ovation
Departures: May 2025 to Oct 2025
Countries Visited: Spain, France, Gibraltar, Morocco (+4 more), Monaco, Italy, Corsica, Sardinia
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$15,418
SUITE
$28,714
From 15,418
View Trip
11 Day Archons, Emperors & Sultans with Regent Seven Seas
Cruise

11 Days (10 Nights) Istanbul to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Navigator
Departure: 05 November 2024
Countries Visited: Turkey, Greece, Sicily, Italy (+1 more), Monaco
Explore More OfferExclusive Deal
INSIDE
-
OCEANVIEW
$5,971
BALCONY
$8,178
SUITE
$9,092
Save 8,739
From 5,971
View Trip
8 Day A Journey From Barcelona To Civitavecchia with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departures: Jun 2025 to Sep 2025
Countries Visited: Spain, France, Italy
Unique EscapesPenthouse Dream Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$5,846
SUITE
$7,108
From 5,846
View Trip
31 Day Tyrrhenian Treasures & Mediterranean Overture with Seabourn
Cruise

31 Days (30 Nights) Monte Carlo to Rome
Cruise Line: Seabourn
Ship: Ovation
Departure: 09 October 2025
Countries Visited: Monaco, Italy, Sicily, Malta (+6 more), Corsica, France, Spain, Gibraltar, Morocco, Sardinia
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$23,001
SUITE
$43,029
From 23,001
View Trip
8 Day Yachting Gems of the French and Italian Rivieras with Emerald Cruises
New ReleaseCruise

8 Days (7 Nights) Nice to Barcelona
Cruise Line: Emerald Cruises
Ships: Emerald Sakara
Departures: Oct 2025 to Aug 2026
Countries Visited: France, Italy, Corsica, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
$6,480
BALCONY
-
SUITE
$8,791
Save 1,576
From 6,480
View Trip
11 Day Mediterranean And Greek Islands with Cunard
Cruise

11 Days (10 Nights) Athens to London
Cruise Line: Cunard
Ship: Queen Anne
Departure: 16 September 2025
Countries Visited: Greece, Sicily, Spain, England
INSIDE
$2,379
OCEANVIEW
$2,973
BALCONY
$3,963
SUITE
$8,814
From 2,379
View Trip
Results: 91-120 of 457

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