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All South America Cruises

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343 Cruises (1,760 Cruise Departures)
13 Day Buenos Aires to Rio De Janeiro with Silversea
Cruise

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 16 December 2025
Countries Visited: Argentina, Uruguay, Brazil
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$11,187
BALCONY
$12,276
SUITE
$20,889
From 11,187
View Trip
6 Day Galapagos at a Glance: Southern Islands (Grand Daphne) with Intrepid Travel
Cruise

6 Days (5 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: May 2024 to Dec 2025
Trip Styles: Group, Cruise, Island Hopping, Short Break, Wildlife
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save 1,050
From 4,167
View Trip
7 Day Independent Galapagos Cruise Aboard the Galapagos Legend with Globus
New ReleaseTour + Cruise

7 Days Quito to Guayaquil
Operated By: Globus
Departures: Aug 2024 to Mar 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 140
From 6,892
View Trip
10 Day Galápagos – West & Central Islands aboard the Reina Silvia Voyager with G Adventures
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: G Adventures
Departures: May 2024 to Dec 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Deal
Save 2,678
From 7,721
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4 Day South America with MSC Cruises
Cruise

4 Days (3 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Nov 2024 to Dec 2024
Countries Visited: Brazil
Save And Sail OfferEarly Booking Offer
INSIDE
$598
OCEANVIEW
$678
BALCONY
$796
SUITE
$1,470
From 598
View Trip
13 Day Patagonia: Edge of the World with Collette
Tour + Cruise

13 Days Buenos Aires to Buenos Aires
Operated By: Collette
Departures: Oct 2024 to Mar 2025
Trip Styles: Adventure, Coach, Small Group, Cruise, Scenic
Countries Visited: Argentina, Chile
Exclusive Savings
Save 223
From 10,169
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30 Day Best of South America with Amazon and Galapagos Cruises with APT
Tour + Cruise

30 Days Santiago to Guayaquil
Operated By: APT
Ship: Delfin III
Departures: Apr 2025 to Sep 2025
Trip Styles: Coach, Group, Cruise, River Cruise, Island Hopping, Scenic
Countries Visited: Chile, Argentina, Brazil, Peru (+2 more), Ecuador, Galapagos
Exclusive Deal
Save 2,739
From 39,656
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14 Day Patagonian Shores & Chilean Fjords with Viking Cruises
Cruise

14 Days (13 Nights) Santiago to Buenos Aires
Cruise Line: Viking Cruises
Ship: Viking Octantis
Departure: 11 November 2024
Countries Visited: Chile, Argentina
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$14,845
SUITE
$20,785
Save 1,150
From 14,845
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15 Day Treasures Of The Pacific Coast - Panama To Chile with Hurtigruten
Cruise

15 Days (14 Nights) Colon to Valparaiso
Cruise Line: Hurtigruten
Ships: MS Fram, MS Roald Amundsen
Departures: Oct 2024 to Oct 2024
Countries Visited: Panama, Ecuador, Peru, Chile
Exclusive Deal
INSIDE
-
OCEANVIEW
$6,549
BALCONY
-
SUITE
$9,145
Save 4,779
From 6,549
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9 Day Lima to Valparaiso with Silversea
Cruise

9 Days (8 Nights) Lima to Valparaiso
Cruise Line: Silversea
Ship: Silver Wind
Departure: 10 November 2024
Countries Visited: Peru, Chile
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
$7,326
BALCONY
$8,712
SUITE
-
From 7,326
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Dec 2024 to Mar 2025
Countries Visited: Brazil
Early Booking OfferSave And Sail Offer
INSIDE
$1,208
OCEANVIEW
$1,386
BALCONY
$1,634
SUITE
$2,762
From 1,208
View Trip
15 Day San Cristóbal to San Cristóbal with Silversea
Cruise

15 Days (14 Nights) Guayaquil to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departures: Oct 2025 to Dec 2025
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$30,987
SUITE
$47,421
From 30,987
View Trip
25 Day Spirit of South America with Santiago and Galapagos Cruise with Globus
Tour + Cruise

25 Days Santiago to Guayaquil
Operated By: Globus
Departure: 12 October 2024
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Chile, Brazil, Argentina, Peru (+2 more), Ecuador, Galapagos
Exclusive Savings
Save 277
From 17,883
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8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Dec 2024 to Mar 2025
Countries Visited: Brazil
Early Booking OfferSave And Sail Offer
INSIDE
$1,208
OCEANVIEW
$1,436
BALCONY
$1,693
SUITE
$2,357
From 1,208
View Trip
7 Day Galapagos Adventure: Northern Islands (Grand Daphne) with Intrepid Travel
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Aug 2024 to Dec 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save 1,322
From 5,356
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13 Day Highlights of Peru with Galápagos Legend North and Central Cruise with Trafalgar
Tour + Cruise

13 Days Lima to Quito
Operated By: Trafalgar
Departures: Jun 2024 to Dec 2024
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador
Exclusive Savings
From 12,301
View Trip
9 Day South America with MSC Cruises
Cruise

9 Days (8 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 28 December 2024
Countries Visited: Brazil
Save And Sail OfferEarly Booking Offer
INSIDE
$2,457
OCEANVIEW
$2,605
BALCONY
$2,883
SUITE
$4,358
From 2,457
View Trip
15 Day Wild Guianas To The Amazon Basin with Seabourn
Cruise

15 Days (14 Nights) Bridgetown to Manaus
Cruise Line: Seabourn
Ship: Venture
Departure: 07 October 2024
Countries Visited: Barbados, Trinidad and Tobago, French Guiana, Brazil
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$18,357
SUITE
$34,851
From 18,357
View Trip
10 Day South America with MSC Cruises
Cruise

10 Days (9 Nights) Montevideo to Montevideo
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 10 March 2025
Countries Visited: Uruguay, Brazil, Argentina
Early Booking OfferSave And Sail Offer
INSIDE
$1,884
OCEANVIEW
$2,142
BALCONY
$2,587
SUITE
-
From 1,884
View Trip
7 Day Galápagos - North & Central Islands aboard the Eden with G Adventures
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: G Adventures
Departures: May 2024 to Dec 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Deal
Save 1,260
From 4,561
View Trip
7 Day South America with MSC Cruises
Cruise

7 Days (6 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 02 February 2025
Countries Visited: Brazil
Save And Sail OfferEarly Booking Offer
INSIDE
$939
OCEANVIEW
$1,098
BALCONY
$1,306
SUITE
$2,424
From 939
View Trip
12 Day Rhythms of the Brazilian Coastline with Scenic
Cruise

12 Days (11 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departures: Nov 2024 to Oct 2025
Countries Visited: Brazil, Uruguay, Argentina
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$10,623
SUITE
$14,365
Save 7,607
From 10,623
View Trip
7 Day Galápagos Land & Sea - Central & South Islands aboard the Yolita with G Adventures
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: G Adventures
Departures: May 2024 to Jun 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Deal
Save 1,885
From 4,102
View Trip
8 Day Lima to Panama City with Silversea
Cruise

8 Days (7 Nights) Lima to Panama City
Cruise Line: Silversea
Ship: Silver Ray
Departure: 04 January 2025
Countries Visited: Peru, Ecuador, Panama
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$4,158
From 4,158
View Trip
10 Day South America with MSC Cruises
Cruise

10 Days (9 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departures: Jan 2025 to Feb 2025
Countries Visited: Argentina, Uruguay, Brazil
Save And Sail OfferEarly Booking Offer
INSIDE
$1,845
OCEANVIEW
$2,112
BALCONY
$2,419
SUITE
$4,043
From 1,845
View Trip
13 Day Valparaiso to Buenos Aires with Silversea
Cruise

13 Days (12 Nights) Valparaiso to Buenos Aires
Cruise Line: Silversea
Ship: Silver Ray
Departure: 09 February 2025
Countries Visited: Argentina, Chile
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$13,117
From 13,117
View Trip
10 Day Galápagos - North, Central, & South Islands aboard the Eden with G Adventures
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: G Adventures
Departures: May 2024 to Dec 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Deal
Save 2,188
From 6,103
View Trip
15 Day Peru & Galapagos by Yacht with Collette
Tour + Cruise

15 Days Lima to Quito
Operated By: Collette
Departures: Sep 2024 to Apr 2025
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
Save 192
From 11,213
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Jan 2025 to Mar 2025
Countries Visited: Brazil, Uruguay, Argentina
Save And Sail OfferEarly Booking Offer
INSIDE
$1,208
OCEANVIEW
$1,436
BALCONY
$1,693
SUITE
$2,357
From 1,208
View Trip
10 Day Heart Of The Amazon with Seabourn
Cruise

10 Days (9 Nights) Manaus to Manaus
Cruise Line: Seabourn
Ship: Venture
Departure: 12 October 2025
Countries Visited: Brazil
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$15,197
SUITE
$29,334
From 15,197
View Trip
Results: 91-120 of 343

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South & Central America Cruises

Amazon Cruises Antarctica Cruises Argentina Cruises Bahamas Cruises Barbados Cruises Bermunda Cruises Brazil Cruises Cape Horn Cruises Caribbean Cruises Central America Cruises Chile Cruises Ecuador Cruises Falkland Island Cruises Falkland Islands Cruises France Cruises Galapagos Cruises Mexico Cruises Morocco Cruises Panama Cruises Panama Cruises Patagonia Cruises Peru Cruises Portugal Cruises South America Cruises South Georgia Island Cruises Spain Cruises Uruguay Cruises

Travel Styles

Coach Tours Luxury Cruises Short Cruise Breaks Wildlife Tours

Cities

Barcelona Bridgetown Buenos Aires Colon Lima Lisbon Malaga Manaus Marseille Papeete Quito Rio de Janeiro San Antonio Santiago Santiago Sao Paulo Valparaiso

Routes

Cruises from Barcelona to Fort Lauderdale Cruises from Barcelona to Lisbon Cruises from Barcelona to London Cruises from Barcelona to Rome Cruises from Barcelona to Barcelona Cruises from Barcelona to Miami Cruises from Bridgetown to Miami Cruises from Bridgetown to Bridgetown Cruises from Buenos Aires to San Antonio Cruises from Buenos Aires to Rio de Janeiro Cruises from Buenos Aires to Buenos Aires Cruises from Dover to Dover Cruises from Fort Lauderdale to Los Angeles Cruises from Fort Lauderdale to London Cruises from Fort Lauderdale to Barcelona Cruises from Fort Lauderdale to Fort Lauderdale Cruises from Fort Lauderdale to San Diego Cruises from Genoa to Genoa Cruises from Hamburg to London Cruises from Hamburg to Hamburg Cruises from Lima to Buenos Aires Cruises from Lima to Quito Cruises from Lisbon to Lisbon Cruises from Lisbon to London Cruises from Lisbon to Miami Cruises from Lisbon to Barcelona Cruises from Lisbon to Rome Cruises from London to Hamburg Cruises from London to Barcelona Cruises from London to Fort Lauderdale Cruises from London to Copenhagen Cruises from London to Rome Cruises from London to London Cruises from London to Lisbon Cruises from London to New York Cruises from Los Angeles to Miami Cruises from Los Angeles to Fort Lauderdale Cruises from Los Angeles to Los Angeles Cruises from Malaga to Malaga Cruises from Marseille to Marseille Cruises from Miami to San Juan Cruises from Miami to Los Angeles Cruises from Miami to Rome Cruises from Miami to Bridgetown Cruises from Miami to Panama City Cruises from Miami to Barcelona Cruises from Miami to Miami Cruises from Miami to London Cruises from Montreal to New York Cruises from New York to New York Cruises from New York to London Cruises from Papeete to Papeete Cruises from Quito to Guayaquil Cruises from Quito to Quito Cruises from Rio de Janeiro to Rio de Janeiro Cruises from Rio de Janeiro to Barcelona Cruises from Rome to London Cruises from Rome to Lisbon Cruises from Rome to Miami Cruises from Rome to Barcelona Cruises from Rome to Fort Lauderdale Cruises from Rome to Rome Cruises from San Antonio to Buenos Aires Cruises from San Juan to San Juan Cruises from Santiago to Santiago Cruises from Sao Paulo to Sao Paulo

Country Routes

Cruises from Peru to Argentina Cruises from USA to Portugal Cruises from USA to Germany Cruises from Italy to England Cruises from Germany to England Cruises from France to Spain Cruises from Portugal to England Cruises from Puerto Rico to USA Cruises from France to Brazil Cruises from France to USA Cruises from England to Canada Cruises from England to Germany Cruises from Brazil to Spain Cruises from USA to Puerto Rico Cruises from Canada to England Cruises from Argentina to Brazil Cruises from Argentina to Chile Cruises from Brazil to Italy Cruises from Argentina to USA Cruises from Barbados to USA Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Denmark Cruises from England to Italy Cruises from England to Spain Cruises from England to USA Cruises from France to Italy Cruises from French Polynesia to USA Cruises from Italy to Brazil Cruises from Italy to France Cruises from Italy to Portugal Cruises from Italy to Spain Cruises from Italy to USA Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Peru to Ecuador Cruises from Portugal to Italy Cruises from Portugal to Spain Cruises from Portugal to USA Cruises from Spain to France Cruises from Spain to Italy Cruises from Spain to Portugal Cruises from Spain to USA Cruises from USA to Argentina Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from England to Portugal Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Holland Cruises from USA to Italy Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Peru Cruises from USA to Spain

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises Hurtigruten South America Cruises MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

South America Tours

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