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Cruises From Santa Cruz de Tenerife

Choose from 57 unique cruises starting in Santa Cruz de Tenerife, and travelling to Barcelona, Bari, Lisbon, Madeira, Miami and more. December is the most popular month to join a cruise from Santa Cruz de Tenerife and you can select from 195 departures available from four leading cruise lines.
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4 Days
21 Days
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57 Cruises (195 Cruise Departures)
21 Day Discover the Yachting Treasures of the Mediterranean with Emerald Cruises
New ReleaseCruise

21 Days (20 Nights) Santa Cruz de Tenerife to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 15 April 2026
Countries Visited: Spain, Morocco, Corsica, Sardinia (+2 more), Sicily, Malta
Exclusive Savings
INSIDE
-
OCEANVIEW
$25,421
BALCONY
-
SUITE
$34,241
Save 519
From 25,421
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Dec 2024 to Dec 2025
Countries Visited: Spain, Portugal
INSIDE
$763
OCEANVIEW
$1,079
BALCONY
$1,345
SUITE
$2,087
From 763
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 21 December 2024
Countries Visited: Spain, Portugal
INSIDE
$1,505
OCEANVIEW
$1,970
BALCONY
$2,404
SUITE
-
From 1,505
View Trip
14 Day Canary Islands And Mediterranean with P&O Cruises Worldwide
Cruise

14 Days (13 Nights) Santa Cruz de Tenerife to Valletta
Ship: Azura
Departure: 20 March 2026
Countries Visited: Spain, Gibraltar, Italy, Sicily (+1 more), Malta
INSIDE
$1,693
OCEANVIEW
$2,087
BALCONY
$2,817
SUITE
$4,598
From 1,693
View Trip
12 Day Canary Islands And Madeira with MSC Cruises
Cruise

12 Days (11 Nights) Santa Cruz de Tenerife to Venice
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 23 March 2025
Countries Visited: Spain, Morocco, Sicily, Greece (+2 more), Italy, Croatia
Save And Sail Offer
INSIDE
$1,567
OCEANVIEW
$1,914
BALCONY
$2,844
SUITE
$4,280
From 1,567
View Trip
21 Day Canary Islands And Mediterranean with P&O Cruises Worldwide
Cruise

21 Days (20 Nights) Santa Cruz de Tenerife to Valletta
Ship: Azura
Departure: 13 March 2026
Countries Visited: Spain, Portugal, Gibraltar, Italy (+2 more), Sicily, Malta
INSIDE
$2,705
OCEANVIEW
$3,402
BALCONY
$4,084
SUITE
-
From 2,705
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 21 December 2024
Countries Visited: Spain, Portugal
INSIDE
-
OCEANVIEW
$4,196
BALCONY
-
SUITE
-
From 4,196
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 27 December 2024
Countries Visited: Spain, Portugal
INSIDE
$2,883
OCEANVIEW
$3,899
BALCONY
$4,451
SUITE
$9,945
From 2,883
View Trip
4 Day Canary Islands And Madeira with MSC Cruises
Cruise

4 Days (3 Nights) Santa Cruz de Tenerife to Madeira
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 03 November 2024
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$857
SUITE
$1,233
From 857
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Nov 2025 to Mar 2026
Countries Visited: Spain, Portugal
INSIDE
$1,633
OCEANVIEW
$2,055
BALCONY
$2,657
SUITE
$4,744
From 1,633
View Trip
10 Day Canary Islands And Madeira with MSC Cruises
Cruise

10 Days (9 Nights) Santa Cruz de Tenerife to Bari
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 23 March 2025
Countries Visited: Spain, Morocco, Sicily, Greece (+1 more), Italy
Save And Sail Offer
INSIDE
$1,748
OCEANVIEW
$2,194
BALCONY
$3,382
SUITE
$5,213
From 1,748
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Oct 2024 to Feb 2025
Countries Visited: Spain, Portugal
INSIDE
$1,497
OCEANVIEW
$1,998
BALCONY
$2,471
SUITE
-
From 1,497
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Nov 2024 to Dec 2025
Countries Visited: Spain, Portugal
INSIDE
$1,626
OCEANVIEW
$2,216
BALCONY
$2,649
SUITE
$7,793
From 1,626
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 27 December 2025
Countries Visited: Spain, Portugal
INSIDE
$1,772
OCEANVIEW
$1,959
BALCONY
$2,621
SUITE
$4,353
From 1,772
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 20 December 2024
Countries Visited: Spain, Portugal
INSIDE
$1,505
OCEANVIEW
$2,039
BALCONY
$2,404
SUITE
-
From 1,505
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Nov 2025 to Feb 2026
Countries Visited: Spain, Portugal
INSIDE
$1,633
OCEANVIEW
$1,976
BALCONY
$2,538
SUITE
$4,299
From 1,633
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 14 December 2024
Countries Visited: Spain, Portugal
INSIDE
$3,309
OCEANVIEW
$3,978
BALCONY
$4,778
SUITE
-
From 3,309
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 20 December 2024
Countries Visited: Spain, Portugal
INSIDE
$3,111
OCEANVIEW
$4,097
BALCONY
$4,778
SUITE
-
From 3,111
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 26 December 2025
Countries Visited: Spain, Portugal
INSIDE
$1,653
OCEANVIEW
$1,959
BALCONY
$2,621
SUITE
$3,927
From 1,653
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Oct 2024 to Oct 2025
Countries Visited: Spain, Portugal
INSIDE
$1,497
OCEANVIEW
$1,998
BALCONY
$2,649
SUITE
$3,936
From 1,497
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 31 October 2025
Countries Visited: Spain, Portugal
INSIDE
$2,059
OCEANVIEW
$2,550
BALCONY
$3,301
SUITE
$5,368
From 2,059
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Oct 2024 to Oct 2025
Countries Visited: Spain, Portugal
INSIDE
$693
OCEANVIEW
$1,049
BALCONY
$1,315
SUITE
$2,157
From 693
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Nov 2025 to Feb 2026
Countries Visited: Spain, Portugal
INSIDE
$1,633
OCEANVIEW
$1,976
BALCONY
$2,538
SUITE
-
From 1,633
View Trip
11 Day Canary Islands & Spanish coast with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Santa Cruz de Tenerife to Barcelona
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 15 April 2026
Countries Visited: Spain, Morocco
Exclusive Savings
INSIDE
-
OCEANVIEW
$12,588
BALCONY
-
SUITE
$16,998
Save 257
From 12,588
View Trip
8 Day Canary Islands And Madeira with MSC Cruises
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 03 November 2024
Countries Visited: Spain, Portugal
Save And Sail Offer
INSIDE
$1,029
OCEANVIEW
$1,247
BALCONY
-
SUITE
$2,840
From 1,029
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Oct 2024 to Oct 2025
Countries Visited: Spain, Portugal
INSIDE
$1,497
OCEANVIEW
$1,998
BALCONY
$2,867
SUITE
-
From 1,497
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 01 November 2025
Countries Visited: Spain, Portugal
INSIDE
$2,059
OCEANVIEW
$2,451
BALCONY
$3,301
SUITE
$5,368
From 2,059
View Trip
8 Day Canary Islands And Madeira with MSC Cruises
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 22 December 2024
Countries Visited: Spain, Portugal
Save And Sail Offer
INSIDE
$1,603
OCEANVIEW
$1,821
BALCONY
$2,494
SUITE
$3,415
From 1,603
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Oct 2024 to Mar 2026
Countries Visited: Spain, Portugal
INSIDE
$693
OCEANVIEW
$969
BALCONY
$1,345
SUITE
$2,157
From 693
View Trip
8 Day Canary Islands And Madeira with MSC Cruises
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 24 November 2024
Countries Visited: Spain, Portugal
Save And Sail Offer
INSIDE
$1,049
OCEANVIEW
$1,247
BALCONY
$1,920
SUITE
$2,840
From 1,049
View Trip
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