Spain Cruises Starting In May 2025

If you're looking at joining a cruise to Spain in May 2025, we have 48 unique cruise itineraries and 666 departures available, operated by fourteen of the world's leading cruise lines departing in May.
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Departures (May 2025)
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5 Days
16 Days
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$100pp
$29,040pp
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48 Cruises (666 Cruise Departures)
Cruise
 (1)

6 Days (5 Nights) Barcelona to Barcelona
Cruise Line: Azamara Cruises
Departure: 22 May 2025
Countries Visited: Spain, France
INSIDE
$2,607
OCEANVIEW
$2,837
BALCONY
$3,527
SUITE
$6,286
From 2,607
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: Royal Caribbean
Departures: Jun 2024 to Oct 2025
Countries Visited: Spain, Italy
Exclusive Deal
INSIDE
$1,602
OCEANVIEW
$2,127
BALCONY
$2,185
SUITE
$3,083
Save 3,282
From 1,406
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Royal Caribbean
Departures: Jun 2024 to Oct 2025
Countries Visited: Italy, Spain
Exclusive Deal
INSIDE
$1,965
OCEANVIEW
$2,450
BALCONY
$2,513
SUITE
$3,549
Save 1,758
From 1,653
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: Royal Caribbean
Departures: Jun 2024 to Oct 2025
Countries Visited: Spain, France, Italy
Exclusive Deal
INSIDE
$1,711
OCEANVIEW
$2,291
BALCONY
$2,329
SUITE
$3,104
Save 1,839
From 1,502
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: May 2024 to Oct 2025
Countries Visited: Italy, Spain, France
Mutiple Deals Available
INSIDE
$1,465
OCEANVIEW
$1,692
BALCONY
$1,890
SUITE
$2,475
From 1,465
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Viking Cruises
Departures: Sep 2024 to Sep 2026
Countries Visited: Italy, Monaco, France, Spain
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$4,450
SUITE
$6,925
Save 1,178
From 4,450
Cruise
 (2)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Departure: 06 May 2025
Countries Visited: Spain, France, Monaco, Italy
Exclusive Deal
INSIDE
$4,129
OCEANVIEW
$4,357
BALCONY
$6,109
SUITE
$8,238
Save 2,031
From 4,129
Cruise
 (2)

9 Days (8 Nights) London to Barcelona
Cruise Line: Royal Caribbean
Departure: 13 May 2025
Countries Visited: England, Spain, Portugal
Exclusive Deal
INSIDE
$2,239
OCEANVIEW
$2,273
BALCONY
$3,335
SUITE
$4,418
Save 831
From 1,921
Cruise

9 Days (8 Nights) London to Rome
Cruise Line: Cunard
Departure: 04 May 2025
Countries Visited: England, Spain, Italy
INSIDE
$1,269
OCEANVIEW
$1,348
BALCONY
$1,586
SUITE
$3,833
From 1,269
Cruise

7 Days (6 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 04 May 2025
Countries Visited: Spain, France, Italy
Early Booking Offer
INSIDE
$1,684
OCEANVIEW
$1,833
BALCONY
$2,021
SUITE
$2,516
From 1,684
Cruise

14 Days (13 Nights) Orlando to Barcelona
Cruise Line: Royal Caribbean
Departure: 03 May 2025
Countries Visited: USA, Portugal, Spain
Exclusive Deal
INSIDE
$1,700
OCEANVIEW
$2,000
BALCONY
$2,973
SUITE
$4,622
Save 655
From 1,497
Cruise

10 Days (9 Nights) Barcelona to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 04 May 2025
Countries Visited: Spain, Portugal, Morocco
Unique Escapes
INSIDE
-
OCEANVIEW
-
BALCONY
$7,049
SUITE
$8,593
From 7,049
Cruise

5 Days (4 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Departure: 02 May 2025
Countries Visited: France, Spain, Italy
Early Booking Offer
INSIDE
$766
OCEANVIEW
$875
BALCONY
$984
SUITE
$1,489
From 766
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 18 May 2025
Countries Visited: Spain, France, Corsica
Up to 80% Off Second Sailor + Free Upgrade
INSIDE
$2,368
OCEANVIEW
$2,758
BALCONY
$3,052
SUITE
$6,742
From 2,368
Cruise

8 Days (7 Nights) London to London
Ship: Ventura
Departures: May 2024 to Oct 2025
Countries Visited: England, Spain, France
INSIDE
$1,139
OCEANVIEW
$1,376
BALCONY
$1,662
SUITE
$2,799
From 1,139
Cruise

6 Days (5 Nights) Genoa to Valencia
Cruise Line: MSC Cruises
Departure: 05 May 2025
Countries Visited: Italy, France, Spain
Exclusive Deal
INSIDE
$804
OCEANVIEW
$933
BALCONY
$1,111
SUITE
$1,992
From 804
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Viking Cruises
Departures: Jun 2024 to Jul 2026
Countries Visited: Spain, France, Monaco, Italy
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$4,450
SUITE
$6,925
Save 1,279
From 4,450
Cruise

10 Days (9 Nights) Barcelona to Barcelona
Departures: Nov 2024 to Oct 2025
Countries Visited: Spain, France, Italy
INSIDE
$2,232
OCEANVIEW
$2,430
BALCONY
$2,507
SUITE
$2,737
From 2,232
Cruise

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: May 2024 to Oct 2025
Countries Visited: Italy, Spain, France
Mutiple Deals Available
INSIDE
$1,465
OCEANVIEW
$1,692
BALCONY
$1,890
SUITE
$2,475
From 1,465
Cruise

8 Days (7 Nights) Barcelona to Valencia
Cruise Line: MSC Cruises
Departure: 03 May 2025
Countries Visited: Spain, Italy, France
Exclusive Deal
INSIDE
$1,068
OCEANVIEW
$1,266
BALCONY
$1,514
SUITE
$2,702
From 1,068
Cruise

5 Days (4 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Departure: 01 May 2025
Countries Visited: Italy, France, Spain
Early Booking Offer
INSIDE
$1,063
OCEANVIEW
$1,172
BALCONY
$1,251
SUITE
$1,766
From 1,063
Cruise

15 Days (14 Nights) London to London
Ships: Britannia, Ventura
Departures: Aug 2024 to Oct 2025
Countries Visited: England, Portugal, Spain
INSIDE
$1,763
OCEANVIEW
$2,135
BALCONY
$2,440
SUITE
$5,597
From 1,763
Cruise

8 Days (7 Nights) London to London
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departures: Jun 2024 to Sep 2026
Countries Visited: England, France, Spain
Best Deal OfferEarly Booking Offer
INSIDE
$1,316
OCEANVIEW
$1,435
BALCONY
$1,603
SUITE
$3,316
From 1,316
Cruise

13 Days (12 Nights) London to London
Cruise Line: Royal Caribbean
Departure: 12 May 2025
Countries Visited: England, Spain, Portugal
Exclusive Deal
INSIDE
$3,204
OCEANVIEW
$3,867
BALCONY
$4,874
SUITE
$7,002
Save 1,227
From 2,757
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Departure: 31 May 2025
Countries Visited: Italy, France, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$9,034
SUITE
$9,766
Save 5,826
From 9,034
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Royal Caribbean
Departures: Jun 2024 to Oct 2025
Countries Visited: Italy, Spain, France
Exclusive Deal
INSIDE
$2,149
OCEANVIEW
$2,599
BALCONY
$2,616
SUITE
$3,709
Save 2,668
From 1,851
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Departures: May 2024 to Sep 2025
Countries Visited: Spain, Italy, France
Best Deal OfferEarly Booking Offer
INSIDE
$1,286
OCEANVIEW
$1,484
BALCONY
$1,652
SUITE
$2,514
From 1,286
Cruise

8 Days (7 Nights) Valencia to Valencia
Cruise Line: MSC Cruises
Departures: May 2024 to Sep 2025
Countries Visited: Spain, Italy, France
Mutiple Deals Available
INSIDE
$1,296
OCEANVIEW
$1,494
BALCONY
$1,673
SUITE
$2,474
From 1,296
Cruise

8 Days (7 Nights) Palma de Mallorca to Palma de Mallorca
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: May 2024 to Oct 2025
Countries Visited: Spain, France, Italy
Mutiple Deals Available
INSIDE
$1,465
OCEANVIEW
$1,692
BALCONY
$1,890
SUITE
$2,475
From 1,465
Cruise

13 Days (12 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 18 May 2025
Countries Visited: Spain, France, Monaco, Italy
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$18,315
From 18,315
Results: 1-30 of 48

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