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All South America Cruises

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315 Cruises (1,596 Cruise Departures)
10 Day South America with MSC Cruises
Cruise

10 Days (9 Nights) Montevideo to Montevideo
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 01 March 2025
Countries Visited: Uruguay, Brazil, Argentina
Save And Sail Offer
INSIDE
$1,894
OCEANVIEW
$2,241
BALCONY
$2,587
SUITE
-
From 1,894
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 08 February 2025
Countries Visited: Brazil
Save And Sail OfferEarly Booking Offer
INSIDE
$1,089
OCEANVIEW
$1,277
BALCONY
$1,515
SUITE
$2,812
From 1,089
View Trip
7 Day Independent Galapagos Cruise Aboard the Galapagos Legend with Globus
New ReleaseTour + Cruise

7 Days Quito to Guayaquil
Operated By: Globus
Departures: Sep 2024 to Mar 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 140
From 6,892
View Trip
9 Day South America with MSC Cruises
Cruise

9 Days (8 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departures: Dec 2024 to Mar 2025
Countries Visited: Argentina, Uruguay, Brazil
Early Booking OfferSave And Sail Offer
INSIDE
$1,526
OCEANVIEW
$1,734
BALCONY
$2,021
SUITE
$3,487
From 1,526
View Trip
8 Day Galapagos: Wildlife Wonderland with Tauck
Cruise

8 Days (7 Nights) Quito to Guayaquil
Operated By: Tauck
Departures: Jun 2025 to Dec 2025
Trip Styles: Group, Cruise, Family, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
From 12,140
View Trip
10 Day Galápagos - East, Central, & West Islands aboard the Eden with G Adventures
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: G Adventures
Departures: Jun 2024 to Dec 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 178
From 8,055
View Trip
8 Day Lima to Panama City with Silversea
Cruise

8 Days (7 Nights) Lima to Panama City
Cruise Line: Silversea
Ship: Silver Ray
Departure: 04 January 2025
Countries Visited: Peru, Ecuador, Panama
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$4,158
From 4,158
View Trip
12 Day Lautoka to Tahiti with Silversea
Cruise

12 Days (11 Nights) Lautoka to Tahiti
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 29 September 2025
Countries Visited: Fiji, Cook Islands, Tonga, French Polynesia
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$22,473
BALCONY
$25,641
SUITE
$38,709
From 22,473
View Trip
7 Day South America with MSC Cruises
Cruise

7 Days (6 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Dec 2024 to Feb 2025
Countries Visited: Brazil
Save And Sail OfferEarly Booking Offer
INSIDE
$939
OCEANVIEW
$1,098
BALCONY
$1,306
SUITE
$2,424
From 939
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) San Cristobal Island to San Cristobal Island
Cruise Line: Silversea
Ship: Silver Origin
Departures: Feb 2026 to Mar 2026
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$20,592
SUITE
$30,591
From 20,592
View Trip
6 Day South America with MSC Cruises
Cruise

6 Days (5 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 09 December 2024
Countries Visited: Brazil
Save And Sail OfferEarly Booking Offer
INSIDE
$908
OCEANVIEW
$1,017
BALCONY
$1,205
SUITE
$2,165
From 908
View Trip
7 Day Galapagos Adventure: Northern Islands (Grand Daphne) with Intrepid Travel
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Aug 2024 to Dec 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 140
From 6,540
View Trip
19 Day Cape Horn Encounter with Oceania Cruises
Cruise

19 Days (18 Nights) San Antonio to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 06 March 2025
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Cabin Upgrade Offer
INSIDE
$8,646
OCEANVIEW
$9,794
BALCONY
$10,715
SUITE
$14,616
From 8,646
View Trip
21 Day Lima to Buenos Aires with Silversea
Cruise

21 Days (20 Nights) Lima to Buenos Aires
Cruise Line: Silversea
Ship: Silver Ray
Departure: 01 February 2025
Countries Visited: Argentina, Chile, Peru
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$25,344
From 25,344
View Trip
17 Day Cape Horn & Strait of Magellan with Princess
Cruise

17 Days (16 Nights) Santiago to Buenos Aires
Cruise Line: Princess
Ship: Sapphire Princess
Departure: 06 December 2025
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Exclusive Deal
INSIDE
$4,617
OCEANVIEW
$4,508
BALCONY
$6,884
SUITE
$8,478
From 4,508
View Trip
17 Day Grand Galapagos (Grand Queen Beatriz) with Intrepid Travel
Cruise

17 Days (16 Nights) Quito to Quito
Operated By: Intrepid Travel
Departure: 28 December 2024
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 376
From 18,407
View Trip
12 Day Wonders of the Galápagos & Machu Picchu: Northern Islands Route with Abercrombie & Kent
New ReleaseTour + Cruise

12 Days Guayaquil to Lima
Operated By: Abercrombie & Kent
Departures: Feb 2025 to Nov 2025
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Ecuador, Galapagos, Peru
From 26,465
View Trip
7 Day Galapagos Express - Central, South & East Islands aboard the Archipel I with Explore!
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: Explore!
Departures: Jun 2024 to Dec 2025
Trip Styles: Small Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 155
From 7,428
View Trip
6 Day Galapagos at a Glance: Southern Islands (Grand Daphne) with Intrepid Travel
Cruise

6 Days (5 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Aug 2024 to Dec 2025
Trip Styles: Group, Cruise, Island Hopping, Short Break, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 112
From 5,256
View Trip
25 Day Spirit of South America with Santiago and Galapagos Cruise with Globus
Tour + Cruise

25 Days Santiago to Guayaquil
Operated By: Globus
Departure: 12 October 2024
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Chile, Brazil, Argentina, Peru (+2 more), Ecuador, Galapagos
Exclusive Savings
Save 277
From 17,883
View Trip
15 Day Treasures Of The Pacific Coast - Panama To Chile with Hurtigruten
Cruise

15 Days (14 Nights) Colon to Valparaiso
Cruise Line: Hurtigruten
Ship: MS Roald Amundsen
Departure: 07 October 2024
Countries Visited: Panama, Ecuador, Peru, Chile
Exclusive Deal
INSIDE
-
OCEANVIEW
$6,549
BALCONY
-
SUITE
$9,145
Save 2,271
From 6,549
View Trip
10 Day Galápagos - North, Central, & South Islands aboard the Eden with G Adventures
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: G Adventures
Departures: Jun 2024 to Dec 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 178
From 8,055
View Trip
9 Day Lima to Valparaiso with Silversea
Cruise

9 Days (8 Nights) Lima to Valparaiso
Cruise Line: Silversea
Ship: Silver Ray
Departure: 01 February 2025
Countries Visited: Chile, Peru
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$7,672
From 7,672
View Trip
8 Day Galápagos - West & Central Islands aboard the Eden with G Adventures
Cruise

8 Days (7 Nights) Quito to Quito
Operated By: G Adventures
Departures: Jun 2024 to Dec 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 135
From 6,095
View Trip
5 Day South America with MSC Cruises
Cruise

5 Days (4 Nights) São Paulo to São Paulo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Nov 2024 to Mar 2025
Countries Visited: Brazil
Save And Sail OfferEarly Booking Offer
INSIDE
$817
OCEANVIEW
$946
BALCONY
$1,095
SUITE
$1,540
From 817
View Trip
17 Day Edge Of The World Expedition with Regent Seven Seas
Cruise

17 Days (16 Nights) Santiago to Buenos Aires
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 01 February 2026
Countries Visited: Chile, Argentina, Uruguay
Land Package Credit
INSIDE
-
OCEANVIEW
-
BALCONY
$18,481
SUITE
$20,115
Save 8,169
From 18,481
View Trip
17 Day Canary Islands Crossing with Regent Seven Seas
Cruise

17 Days (16 Nights) Rio de Janeiro to Lisbon
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 13 March 2025
Countries Visited: Brazil, Cape Verde, Spain, Portugal
Non-Use Land Package Credit
INSIDE
-
OCEANVIEW
-
BALCONY
$10,831
SUITE
$12,316
Save 5,659
From 10,831
View Trip
34 Day Hamburg To Rio De Janeiro with Cunard
Cruise

34 Days (33 Nights) Hamburg to Rio de Janeiro
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 04 January 2025
Countries Visited: Germany, Holland, Belgium, England (+5 more), Portugal, USA, Turks and Caicos Islands, Barbados, Brazil
Exclusive Deal
INSIDE
$8,216
OCEANVIEW
$9,614
BALCONY
$12,584
SUITE
$28,721
From 8,216
View Trip
18 Day MSC Grand Voyages with MSC Cruises
Cruise

18 Days (17 Nights) Barcelona to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 12 November 2024
Countries Visited: Spain, Morocco, Brazil
Save And Sail Offer
INSIDE
$1,795
OCEANVIEW
$2,033
BALCONY
$2,627
SUITE
-
From 1,795
View Trip
16 Day Portugal, Argentina Transatlantic with Celebrity Cruises
Cruise

16 Days (15 Nights) Lisbon to Buenos Aires
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 21 November 2025
Countries Visited: Portugal, Spain, Brazil, Uruguay (+1 more), Argentina
Exclusive Offer
INSIDE
$2,342
OCEANVIEW
$2,321
BALCONY
$2,611
SUITE
$11,060
Save 3,396
From 2,321
View Trip
Results: 151-180 of 315

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South & Central America Cruises

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Travel Styles

Coach Tours Locally Guided Tours Luxury Cruises Short Cruise Breaks Wildlife Tours

Cities

Barcelona Bridgetown Buenos Aires Lima Lisbon Manaus Marseille Panama City Papeete Quito Rio de Janeiro San Antonio Santiago Santiago Sao Paulo

Routes

Cruises from Barcelona to Fort Lauderdale Cruises from Barcelona to Lisbon Cruises from Barcelona to London Cruises from Barcelona to Rome Cruises from Barcelona to Barcelona Cruises from Barcelona to Miami Cruises from Bridgetown to Miami Cruises from Bridgetown to Bridgetown Cruises from Buenos Aires to Buenos Aires Cruises from Fort Lauderdale to Los Angeles Cruises from Fort Lauderdale to London Cruises from Fort Lauderdale to Barcelona Cruises from Fort Lauderdale to Fort Lauderdale Cruises from Fort Lauderdale to San Diego Cruises from Genoa to Genoa Cruises from Hamburg to London Cruises from Hamburg to Hamburg Cruises from Lima to Buenos Aires Cruises from Lima to Quito Cruises from Lisbon to Lisbon Cruises from Lisbon to Miami Cruises from Lisbon to Barcelona Cruises from Lisbon to Rome Cruises from London to Hamburg Cruises from London to Barcelona Cruises from London to Fort Lauderdale Cruises from London to Rome Cruises from London to London Cruises from London to Lisbon Cruises from London to New York Cruises from Los Angeles to Miami Cruises from Los Angeles to Los Angeles Cruises from Marseille to Marseille Cruises from Miami to San Juan Cruises from Miami to Los Angeles Cruises from Miami to Rome Cruises from Miami to Bridgetown Cruises from Miami to Panama City Cruises from Miami to Barcelona Cruises from Miami to Miami Cruises from Miami to London Cruises from Montreal to New York Cruises from New York to New York Cruises from New York to London Cruises from Panama City to Miami Cruises from Papeete to Papeete Cruises from Quito to Guayaquil Cruises from Quito to Quito Cruises from Rio de Janeiro to Rio de Janeiro Cruises from Rio de Janeiro to Barcelona Cruises from Rome to Lisbon Cruises from Rome to Miami Cruises from Rome to Barcelona Cruises from Rome to Fort Lauderdale Cruises from Rome to Rome Cruises from San Antonio to Buenos Aires Cruises from San Juan to San Juan Cruises from Santiago to Santiago Cruises from Sao Paulo to Sao Paulo

Country Routes

Cruises from Peru to Argentina Cruises from USA to Portugal Cruises from USA to Germany Cruises from Italy to England Cruises from Germany to England Cruises from France to Spain Cruises from Portugal to England Cruises from Puerto Rico to USA Cruises from France to Brazil Cruises from France to USA Cruises from England to Canada Cruises from England to Germany Cruises from Brazil to Spain Cruises from USA to Puerto Rico Cruises from Canada to England Cruises from Argentina to Chile Cruises from Brazil to Italy Cruises from Argentina to USA Cruises from Barbados to USA Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Italy Cruises from England to Spain Cruises from England to USA Cruises from France to Italy Cruises from French Polynesia to USA Cruises from Italy to Brazil Cruises from Italy to France Cruises from Italy to Portugal Cruises from Italy to Spain Cruises from Italy to USA Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Peru to Ecuador Cruises from Portugal to Italy Cruises from Portugal to Spain Cruises from Portugal to USA Cruises from Spain to France Cruises from Spain to Italy Cruises from Spain to Portugal Cruises from Spain to USA Cruises from USA to Argentina Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from England to Portugal Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Holland Cruises from USA to Italy Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Peru Cruises from USA to Spain

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises Hurtigruten South America Cruises MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

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