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Spain Cruises Starting In September 2025

If you're looking at joining a cruise to Spain in September 2025, we have 42 unique cruise itineraries and 675 departures available, operated by twelve of the world's leading cruise lines departing in September.
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Departures (September 2025)
< August 2025 October 2025 >
Duration
8 Days
17 Days
Countries Visited
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$29,040pp
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42 Cruises (675 Cruise Departures)
9 Day Cruising Southern Spain and Portugal - with Smithsonian Journeys with Ponant
Cruise
 (2)

9 Days (8 Nights) Barcelona to Lisbon
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 16 September 2025
Countries Visited: Spain, Portugal
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$9,439
SUITE
$15,917
Save 181
From 9,439
View Trip
9 Day Iberian Shores with Ponant
Cruise
 (2)

9 Days (8 Nights) Lisbon to Barcelona
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 24 September 2025
Countries Visited: Portugal, Spain
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$6,568
SUITE
$12,311
Save 122
From 6,568
View Trip
8 Day Western Mediterranean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Royal Caribbean
Ships: Allure of the Seas, Oasis of the Seas
Departures: Jun 2024 to Oct 2025
Countries Visited: Italy, Spain
Exclusive Deal
INSIDE
$2,075
OCEANVIEW
$2,415
BALCONY
$2,635
SUITE
$3,577
Save 1,611
From 1,770
View Trip
8 Day Western Mediterranean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: Royal Caribbean
Ships: Allure of the Seas, Oasis of the Seas
Departures: Jun 2024 to Oct 2025
Countries Visited: Spain, Italy
Exclusive Deal
INSIDE
$1,691
OCEANVIEW
$2,225
BALCONY
$2,316
SUITE
$2,820
Save 1,550
From 1,399
View Trip
9 Day Civitavecchia to Barcelona with Silversea
Cruise

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 23 September 2025
Countries Visited: Italy, Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$12,078
From 12,078
View Trip
8 Day Western Mediterranean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: Royal Caribbean
Ships: Allure of the Seas, Oasis of the Seas
Departures: May 2024 to Oct 2025
Countries Visited: Spain, France, Italy
Exclusive Deal
INSIDE
$1,827
OCEANVIEW
$2,326
BALCONY
$2,513
SUITE
$3,083
Save 2,026
From 1,481
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: May 2024 to Oct 2025
Countries Visited: Italy, Spain, France
Mutiple Deals Available
INSIDE
$1,465
OCEANVIEW
$1,692
BALCONY
$1,890
SUITE
$2,475
From 1,465
View Trip
8 Day Iconic Western Mediterranean with Viking Cruises
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+8 more), Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Venus, Viking Vesta
Departures: Sep 2024 to Sep 2026
Countries Visited: Italy, Monaco, France, Spain
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$4,450
SUITE
$6,925
Save 1,178
From 4,450
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15 Day Istanbul And Greek Islands with Cunard
Cruise

15 Days (14 Nights) Barcelona to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 29 September 2025
Countries Visited: Spain, Greece, Turkey
INSIDE
$2,875
OCEANVIEW
$3,271
BALCONY
$3,766
SUITE
$7,924
From 2,875
View Trip
15 Day Mediterranean with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) London to London
Ship: Arvia
Departures: Mar 2025 to Sep 2025
Countries Visited: England, Spain, France
INSIDE
$2,189
OCEANVIEW
$2,749
BALCONY
$3,014
SUITE
$4,229
From 2,189
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Valencia to Valencia
Cruise Line: MSC Cruises
Ships: MSC Fantasia, MSC Magnifica
Departures: May 2024 to Sep 2025
Countries Visited: Spain, Italy, France
Mutiple Deals Available
INSIDE
$1,296
OCEANVIEW
$1,494
BALCONY
$1,673
SUITE
$2,474
From 1,296
View Trip
8 Day A Journey From Barcelona To Civitavecchia with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departures: Jun 2025 to Sep 2025
Countries Visited: Spain, France, Italy
INSIDE
-
OCEANVIEW
-
BALCONY
$6,534
SUITE
$7,945
From 5,846
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ships: MSC Fantasia, MSC Magnifica
Departures: May 2024 to Sep 2025
Countries Visited: Spain, Italy, France
Best Deal OfferEarly Booking Offer
INSIDE
$1,286
OCEANVIEW
$1,484
BALCONY
$1,652
SUITE
$2,514
From 1,286
View Trip
14 Day Mediterranean with P&O Cruises Worldwide
Cruise

14 Days (13 Nights) London to London
Ship: Arvia
Departure: 28 September 2025
Countries Visited: England, Spain, France
INSIDE
$2,041
OCEANVIEW
$2,512
BALCONY
$2,977
SUITE
$4,153
From 2,041
View Trip
8 Day Western Mediterranean with Cunard
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 01 September 2025
Countries Visited: Italy, France, Spain
INSIDE
$1,427
OCEANVIEW
$1,645
BALCONY
$1,873
SUITE
$3,833
From 1,427
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Fantasia, MSC Magnifica
Departures: May 2024 to Sep 2025
Countries Visited: Italy, France, Spain
Mutiple Deals Available
INSIDE
$1,256
OCEANVIEW
$1,494
BALCONY
$1,673
SUITE
$2,395
From 1,256
View Trip
10 Day Spanish Flair Cruise with Royal Caribbean
Cruise

10 Days (9 Nights) London to London
Cruise Line: Royal Caribbean
Ships: Anthem of the Seas, Independence of the Seas
Departures: Aug 2024 to Sep 2025
Countries Visited: England, Spain, Portugal
Exclusive Deal
INSIDE
$2,300
OCEANVIEW
$2,894
BALCONY
$3,634
SUITE
$4,792
Save 1,325
From 2,015
View Trip
12 Day Canaries & Portugal Cruise with Celebrity Cruises
Cruise

12 Days (11 Nights) London to London
Cruise Line: Celebrity Cruises
Ship: Celebrity Apex
Departure: 27 September 2025
Countries Visited: England, Portugal, Spain
Exclusive DealExclusive Offer
INSIDE
$2,522
OCEANVIEW
$2,570
BALCONY
$3,371
SUITE
$8,630
Save 3,437
From 2,522
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) London to London
Ships: Britannia, Ventura
Departures: Sep 2025 to Oct 2025
Countries Visited: England, Portugal, Spain
INSIDE
$1,862
OCEANVIEW
$2,650
BALCONY
$2,440
SUITE
$5,083
From 1,862
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: May 2024 to Oct 2025
Countries Visited: Italy, Spain, France
Mutiple Deals Available
INSIDE
$1,465
OCEANVIEW
$1,692
BALCONY
$1,890
SUITE
$2,475
From 1,465
View Trip
10 Day Europe - Western Mediterranean with Norwegian Cruise Line
Cruise

10 Days (9 Nights) Barcelona to Barcelona
Ships: Norwegian Breakaway, Norwegian Escape
Departures: Nov 2024 to Sep 2025
Countries Visited: Spain, Italy, France
INSIDE
$2,296
OCEANVIEW
$2,613
BALCONY
$2,690
SUITE
$2,997
From 2,296
View Trip
15 Day Portugal And Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) London to London
Ship: Iona
Departure: 20 September 2025
Countries Visited: England, Portugal, Spain
INSIDE
$2,752
OCEANVIEW
$3,263
BALCONY
$3,875
SUITE
$5,405
From 2,752
View Trip
8 Day Western Mediterranean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Royal Caribbean
Ships: Allure of the Seas, Oasis of the Seas
Departures: May 2024 to Oct 2025
Countries Visited: Italy, Spain, France
Exclusive Deal
INSIDE
$2,204
OCEANVIEW
$2,647
BALCONY
$2,787
SUITE
$3,952
Save 2,291
From 1,920
View Trip
10 Day Italian Riviera & France Cruise with Celebrity Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: May 2025 to Oct 2025
Countries Visited: Italy, France, Spain
Exclusive DealExclusive Offer
INSIDE
$2,197
OCEANVIEW
$2,706
BALCONY
$2,648
SUITE
$7,960
Save 3,574
From 2,197
View Trip
11 Day Flamenco & Jaleo with Regent Seven Seas
Cruise

11 Days (10 Nights) Lisbon to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 14 September 2025
Countries Visited: Portugal, Spain, France
Exclusive Solo OfferExclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$10,872
SUITE
$13,386
Save 7,548
From 10,872
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: May 2024 to Nov 2025
Countries Visited: Spain, France, Italy
Mutiple Deals Available
INSIDE
$1,465
OCEANVIEW
$1,692
BALCONY
$1,890
SUITE
$2,475
From 1,465
View Trip
9 Day Monte Carlo to Rome with Silversea
Cruise

9 Days (8 Nights) Monte Carlo to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 07 September 2025
Countries Visited: Monaco, France, Spain, Italy
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$11,286
From 11,286
View Trip
15 Day Northern Europe with MSC Cruises
Cruise

15 Days (14 Nights) London to London
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departures: Jul 2024 to Jul 2026
Countries Visited: England, Spain, Portugal
Best Deal OfferEarly Booking Offer
INSIDE
$1,929
OCEANVIEW
$2,087
BALCONY
$2,543
SUITE
$4,542
From 1,929
View Trip
8 Day Spain & France Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) London to London
Cruise Line: Royal Caribbean
Ship: Independence of the Seas
Departure: 22 September 2025
Countries Visited: England, France, Spain
Exclusive Deal
INSIDE
$1,672
OCEANVIEW
$2,143
BALCONY
$2,672
SUITE
$3,543
Save 665
From 1,470
View Trip
10 Day Spain, Portugal & Morocco Cruise with Celebrity Cruises
Cruise

10 Days (9 Nights) Barcelona to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: Jul 2024 to Oct 2025
Countries Visited: Spain, Portugal, Morocco
Exclusive DealExclusive Offer
INSIDE
$2,044
OCEANVIEW
$2,696
BALCONY
$2,667
SUITE
$7,759
Save 3,655
From 1,958
View Trip
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Travel Styles

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Trip Lengths

10 Day 2 Week 3 Day 7 Day

Departure Months

May 2024 June 2024 July 2024 August 2024 September 2024 October 2024 November 2024 December 2024 January 2025 February 2025 March 2025 April 2025 May 2025 June 2025 July 2025 August 2025 September 2025 October 2025 November 2025 December 2025 January 2026 February 2026 March 2026 April 2026 May 2026 June 2026 July 2026 August 2026 September 2026 October 2026 November 2026 December 2026

Cities

Barcelona Las Palmas de Gran Canaria Malaga Santa Cruz de Tenerife Tenerife Valencia

Routes

Athens to Barcelona Barcelona to Nice Barcelona to Fort Lauderdale Barcelona to Istanbul Barcelona to Athens Barcelona to Lisbon Barcelona to London Barcelona to Monte Carlo Barcelona to Rome Barcelona to Venice Barcelona to Barcelona Barcelona to Miami Fort Lauderdale to Barcelona Istanbul to Barcelona Lisbon to Barcelona London to Barcelona Malaga to Malaga Miami to Barcelona Monte Carlo to Barcelona Rio de Janeiro to Barcelona Rome to Barcelona Santa Cruz de Tenerife to Santa Cruz de Tenerife Santa Cruz de Tenerife to Valletta Tenerife to Tenerife Trieste to Barcelona Valletta to Santa Cruz de Tenerife Venice to Barcelona

Country Routes

Brazil to Spain England to Spain France to Spain Greece to Spain Italy to Spain Malta to Spain Monaco to Spain Portugal to Spain Spain to United Arab Emirates Spain to Monaco Spain to Turkey Spain to Brazil Spain to France Spain to Greece Spain to Italy Spain to Malta Spain to Portugal Spain to USA Spain to England Turkey to Spain USA to Spain

Cruise Lines Exploring Europe

APT Europe Cruises Azamara Europe Cruises Celebrity Europe Cruises Cunard Europe Cruises Emerald Europe Cruises G Adventures Europe Cruises Intrepid Europe Cruises MSC Europe Cruises NCL Europe Cruises Oceania Europe Cruises P&O (UK) Europe Cruises Princess Europe Cruises Regent Seven Seas Europe Cruises Royal Caribbean Europe Cruises Scenic Europe Cruises Silversea Europe Cruises Viking Europe Cruises Virgin Voyages Europe Cruises

Western Europe Tours

France Tours Morocco Tours Portugal Tours Provence Tours Spain & Portugal Tours Spain Tours Western Europe Tours

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