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331 Cruises (1,764 Cruise Departures)
47 Day The Americas, Chile & Antarctica with Viking Cruises
Cruise

47 Days (46 Nights) Fort Lauderdale to Buenos Aires
Cruise Line: Viking Cruises
Ship: Viking Octantis
Departure: 13 October 2025
Countries Visited: USA, Mexico, Panama, Ecuador (+6 more), Peru, Chile, Argentina, Antarctica, South Georgia Island, Falkland Islands
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$52,465
SUITE
$79,195
Save 2,530
From 52,465
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43 Day Iconic Isles To Icebergs with Oceania Cruises
Cruise

43 Days (42 Nights) Miami to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 29 November 2025
Countries Visited: USA, Mexico, Belize, Guatemala (+9 more), Honduras, Costa Rica, Panama, Ecuador, Peru, Chile, Argentina, Antarctica, Falkland Islands
Exclusive Deal
INSIDE
$18,251
OCEANVIEW
$21,003
BALCONY
$23,756
SUITE
$34,368
Save 2,129
From 18,251
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise

20 Days (19 Nights) Genoa to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 16 November 2024
Countries Visited: Italy, France, Spain, Portugal (+1 more), Brazil
Save And Sail OfferEarly Booking Offer
INSIDE
$1,911
OCEANVIEW
$2,307
BALCONY
$2,703
SUITE
$7,128
From 1,911
View Trip
42 Day The Americas & Antarctic Explorer with Viking Cruises
Cruise

42 Days (41 Nights) Fort Lauderdale to Buenos Aires
Cruise Line: Viking Cruises
Ship: Viking Octantis
Departure: 25 October 2024
Countries Visited: USA, Mexico, Panama, Ecuador (+4 more), Peru, Chile, Argentina, Antarctica
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$46,525
SUITE
$64,345
Save 2,470
From 46,525
View Trip
39 Day Sunlit Strands & Icy Lands with Oceania Cruises
Cruise

39 Days (38 Nights) Miami to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 07 December 2024
Countries Visited: USA, Mexico, Belize, Honduras (+9 more), Costa Rica, Panama, Ecuador, Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$20,100
SUITE
$29,455
Save 2,150
From 20,100
View Trip
41 Day The Americas & Antarctic Explorer with Viking Cruises
Cruise

41 Days (40 Nights) Fort Lauderdale to Buenos Aires
Cruise Line: Viking Cruises
Ship: Viking Polaris
Departures: Oct 2024 to Oct 2025
Countries Visited: USA, Mexico, Panama, Ecuador (+4 more), Peru, Chile, Argentina, Antarctica
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$45,436
SUITE
$64,345
Save 2,459
From 45,436
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise

19 Days (18 Nights) Sao Paulo to Genoa
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 18 April 2025
Countries Visited: Brazil, Spain, France, Italy
Save And Sail OfferEarly Booking Offer
INSIDE
$2,155
OCEANVIEW
$2,491
BALCONY
$2,986
SUITE
$4,461
From 2,155
View Trip
34 Day Samba & Flamenco Rhythms with Oceania Cruises
Cruise

34 Days (33 Nights) Rio de Janeiro to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 05 April 2025
Countries Visited: Brazil, Cape Verde, Senegal, Spain (+4 more), Portugal, Morocco, Gibraltar, France
Exclusive Deal
INSIDE
$13,990
OCEANVIEW
-
BALCONY
$19,029
SUITE
$25,593
Save 2,100
From 13,990
View Trip
54 Day Ultimate Antarctica & South America Adventure with Princess
Cruise

54 Days (53 Nights) Los Angeles to Buenos Aires
Cruise Line: Princess
Ship: Sapphire Princess
Departure: 16 November 2025
Countries Visited: USA, Mexico, Costa Rica, Panama (+7 more), Ecuador, Peru, Chile, Argentina, Falkland Islands, Uruguay, Antarctica
INSIDE
$14,708
OCEANVIEW
$14,926
BALCONY
$20,153
SUITE
$24,440
From 14,708
View Trip
21 Day MSC Grand Voyages with MSC Cruises
Cruise

21 Days (20 Nights) Rio de Janeiro to Genoa
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 06 April 2025
Countries Visited: Brazil, Spain, Morocco, France (+1 more), Italy
Save And Sail OfferEarly Booking Offer
INSIDE
$2,563
OCEANVIEW
$2,979
BALCONY
$3,464
SUITE
$12,394
From 2,563
View Trip
18 Day MSC Grand Voyages with MSC Cruises
Cruise

18 Days (17 Nights) Rio de Janeiro to Genoa
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 09 March 2025
Countries Visited: Brazil, Cape Verde, Morocco, Spain (+2 more), France, Italy
Save And Sail OfferEarly Booking Offer
INSIDE
$2,014
OCEANVIEW
$2,331
BALCONY
$2,846
SUITE
$5,529
From 2,014
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise

22 Days (21 Nights) Rio de Janeiro to Rome
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 06 April 2025
Countries Visited: Brazil, Spain, Morocco, France (+1 more), Italy
Save And Sail OfferEarly Booking Offer
INSIDE
$2,713
OCEANVIEW
$3,148
BALCONY
$3,633
SUITE
$7,910
From 2,713
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise

19 Days (18 Nights) Genoa to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 21 October 2024
Countries Visited: Italy, Spain, Morocco, Brazil
Save And Sail OfferEarly Booking Offer
INSIDE
-
OCEANVIEW
$2,784
BALCONY
$3,279
SUITE
$4,754
From 2,784
View Trip
21 Day MSC Grand Voyages with MSC Cruises
Cruise

21 Days (20 Nights) Barcelona to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 19 October 2024
Countries Visited: Spain, France, Italy, Morocco (+1 more), Brazil
Save And Sail OfferEarly Booking Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$3,642
SUITE
$5,295
From 3,642
View Trip
18 Day MSC Grand Voyages with MSC Cruises
Cruise

18 Days (17 Nights) Rome to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 22 October 2024
Countries Visited: Italy, Spain, Morocco, Brazil
Save And Sail OfferEarly Booking Offer
INSIDE
-
OCEANVIEW
$2,656
BALCONY
$3,201
SUITE
$4,518
From 2,656
View Trip
27 Day MSC Grand Voyages with MSC Cruises
Cruise

27 Days (26 Nights) Montevideo to Berlin
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 04 April 2025
Countries Visited: Uruguay, Brazil, Spain, Portugal (+5 more), England, France, Holland, Denmark, Germany
Save And Sail Offer
INSIDE
$3,342
OCEANVIEW
$3,877
BALCONY
$4,768
SUITE
-
From 3,342
View Trip
39 Day Grand World Voyage with Holland America
Cruise

39 Days (38 Nights) Fort Lauderdale to Sydney
Cruise Line: Holland America
Ship: Zuiderdam
Departure: 04 January 2025
Countries Visited: USA, Cayman Islands, Costa Rica, Ecuador (+9 more), Peru, Chile, Easter Island, Pitcairn Islands, French Polynesia, Cook Islands, Tonga, New Caledonia, Australia
Exclusive Deal
INSIDE
$12,354
OCEANVIEW
$13,245
BALCONY
$17,700
SUITE
$23,145
From 12,354
View Trip
27 Day MSC Grand Voyages with MSC Cruises
Cruise

27 Days (26 Nights) Buenos Aires to Copenhagen
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 03 April 2025
Countries Visited: Argentina, Uruguay, Brazil, Spain (+5 more), Portugal, England, France, Holland, Denmark
Save And Sail Offer
INSIDE
-
OCEANVIEW
$3,996
BALCONY
-
SUITE
-
From 3,996
View Trip
28 Day MSC Grand Voyages with MSC Cruises
Cruise

28 Days (27 Nights) Buenos Aires to Berlin
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 03 April 2025
Countries Visited: Argentina, Uruguay, Brazil, Spain (+6 more), Portugal, England, France, Holland, Denmark, Germany
Save And Sail OfferEarly Booking Offer
INSIDE
$3,581
OCEANVIEW
$4,146
BALCONY
$4,779
SUITE
$9,343
From 3,581
View Trip
26 Day MSC Grand Voyages with MSC Cruises
Cruise

26 Days (25 Nights) Montevideo to Copenhagen
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 04 April 2025
Countries Visited: Uruguay, Brazil, Spain, Portugal (+4 more), England, France, Holland, Denmark
Save And Sail Offer
INSIDE
$3,252
OCEANVIEW
$3,767
BALCONY
$4,638
SUITE
-
From 3,252
View Trip
25 Day MSC Grand Voyages with MSC Cruises
Cruise

25 Days (24 Nights) Buenos Aires to Rotterdam
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 03 April 2025
Countries Visited: Argentina, Uruguay, Brazil, Spain (+4 more), Portugal, England, France, Holland
Save And Sail Offer
INSIDE
-
OCEANVIEW
$3,667
BALCONY
$4,785
SUITE
-
From 3,667
View Trip
37 Day Southbound To The Amazon with Oceania Cruises
Cruise
 (1)

37 Days (36 Nights) Montreal to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 28 October 2024
Countries Visited: Canada, USA, Antigua and Barbuda, Saint Lucia (+8 more), Grenada, Trinidad and Tobago, Brazil, Barbados, Dominica, Virgin Islands, Puerto Rico, Bahamas
Exclusive Deal
INSIDE
$14,882
OCEANVIEW
$16,100
BALCONY
$21,595
SUITE
-
Save 2,088
From 14,882
View Trip
76 Day South America with P&O Cruises Worldwide
Cruise

76 Days (75 Nights) London to London
Ship: Aurora
Departure: 03 January 2026
Countries Visited: England, Spain, Cape Verde, Brazil (+14 more), Uruguay, Falkland Islands, Chile, Peru, Ecuador, Panama, Colombia, Aruba, Grenada, Barbados, Saint Lucia, Antigua and Barbuda, Sint Maarten, Portugal
INSIDE
$15,796
OCEANVIEW
$20,140
BALCONY
$30,025
SUITE
$63,421
From 15,796
View Trip
62 Day Longitudinal World Cruise IV with Viking Cruises
Cruise

62 Days (61 Nights) Milwaukee to Buenos Aires
Cruise Line: Viking Cruises
Ship: Viking Polaris
Departures: Oct 2024 to Sep 2025
Countries Visited: USA, Canada, Mexico, Panama (+5 more), Ecuador, Peru, Chile, Antarctica, Argentina
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$79,669
SUITE
-
Save 1,740
From 79,669
View Trip
69 Day Longitudinal World Cruise V with Viking Cruises
Cruise

69 Days (68 Nights) Buenos Aires to Milwaukee
Cruise Line: Viking Cruises
Ship: Viking Octantis
Departure: 20 February 2025
Countries Visited: Argentina, Falkland Islands, South Georgia Island, Antarctica (+7 more), Chile, Peru, Ecuador, Panama, Mexico, USA, Canada
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$93,095
SUITE
$132,295
Save 1,900
From 93,095
View Trip
63 Day Longitudinal World Cruise VII with Viking Cruises
Cruise

63 Days (62 Nights) Buenos Aires to Milwaukee
Cruise Line: Viking Cruises
Ship: Viking Polaris
Departure: 21 February 2026
Countries Visited: Argentina, Antarctica, Chile, Peru (+5 more), Panama, Jamaica, Bahamas, USA, Canada
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$86,235
SUITE
$118,575
Save 1,760
From 86,235
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87 Day From the Arctic to Antarctica with Viking Cruises
Cruise

87 Days (86 Nights) Nuuk to Buenos Aires
Cruise Line: Viking Cruises
Ship: Viking Polaris
Departure: 17 September 2026
Countries Visited: Greenland, Canada, USA, Bahamas (+9 more), Mexico, Jamaica, Panama, Peru, Chile, Antarctica, South Georgia Island, Falkland Islands, Argentina
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$121,270
SUITE
$177,700
Save 3,225
From 121,270
View Trip
87 Day From the Arctic to Antarctica with Viking Cruises
Cruise

87 Days (86 Nights) Nuuk to Buenos Aires
Cruise Line: Viking Cruises
Ship: Viking Octantis
Departure: 03 September 2025
Countries Visited: Greenland, Canada, USA, Mexico (+8 more), Panama, Ecuador, Peru, Chile, Argentina, Antarctica, South Georgia Island, Falkland Islands
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$108,400
SUITE
$256,900
Save 3,095
From 108,400
View Trip
87 Day Grand Voyage: Pole To Pole with Holland America
Cruise

87 Days (86 Nights) Buenos Aires to Fort Lauderdale
Cruise Line: Holland America
Ship: Volendam
Departure: 13 March 2025
Countries Visited: Argentina, Uruguay, Brazil, French Guiana (+15 more), Cape Verde, Gambia, Senegal, Spain, Morocco, Gibraltar, Portugal, France, Belgium, Scotland, Norway, Iceland, Greenland, Canada, USA
Exclusive Deal
INSIDE
$29,267
OCEANVIEW
$31,346
BALCONY
$56,888
SUITE
$97,429
From 29,267
View Trip
69 Day Longitudinal World Cruise VI with Viking Cruises
Cruise

69 Days (68 Nights) Buenos Aires to Milwaukee
Cruise Line: Viking Cruises
Ship: Viking Octantis
Departure: 24 February 2026
Countries Visited: Argentina, Falkland Islands, South Georgia Island, Antarctica (+7 more), Chile, Peru, Panama, Jamaica, Bahamas, USA, Canada
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$93,095
SUITE
$132,295
Save 1,900
From 93,095
View Trip
Results: 301-330 of 331

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South & Central America Cruises

Amazon Cruises Antarctica Cruises Argentina Cruises Bahamas Cruises Barbados Cruises Bermunda Cruises Brazil Cruises Cape Horn Cruises Caribbean Cruises Central America Cruises Chile Cruises Ecuador Cruises Falkland Island Cruises Falkland Islands Cruises France Cruises Galapagos Cruises Mexico Cruises Morocco Cruises Panama Cruises Panama Cruises Patagonia Cruises Peru Cruises Portugal Cruises South America Cruises South Georgia Island Cruises Spain Cruises Uruguay Cruises

Travel Styles

Coach Tours Locally Guided Tours Luxury Cruises Short Cruise Breaks Wildlife Tours

Cities

Barcelona Bridgetown Buenos Aires Colon Lima Lisbon Manaus Marseille Papeete Quito Rio de Janeiro San Antonio Santiago Santiago Sao Paulo

Routes

Cruises from Barcelona to Fort Lauderdale Cruises from Barcelona to Lisbon Cruises from Barcelona to London Cruises from Barcelona to Rome Cruises from Barcelona to Barcelona Cruises from Barcelona to Miami Cruises from Bridgetown to Miami Cruises from Bridgetown to Bridgetown Cruises from Buenos Aires to San Antonio Cruises from Buenos Aires to Buenos Aires Cruises from Dover to Dover Cruises from Fort Lauderdale to Los Angeles Cruises from Fort Lauderdale to London Cruises from Fort Lauderdale to Barcelona Cruises from Fort Lauderdale to Fort Lauderdale Cruises from Fort Lauderdale to San Diego Cruises from Genoa to Genoa Cruises from Hamburg to London Cruises from Hamburg to Hamburg Cruises from Lima to Buenos Aires Cruises from Lima to Quito Cruises from Lisbon to Lisbon Cruises from Lisbon to London Cruises from Lisbon to Miami Cruises from Lisbon to Barcelona Cruises from Lisbon to Rome Cruises from London to Hamburg Cruises from London to Barcelona Cruises from London to Fort Lauderdale Cruises from London to Copenhagen Cruises from London to Rome Cruises from London to London Cruises from London to Lisbon Cruises from London to New York Cruises from Los Angeles to Miami Cruises from Los Angeles to Fort Lauderdale Cruises from Los Angeles to Los Angeles Cruises from Marseille to Marseille Cruises from Miami to San Juan Cruises from Miami to Los Angeles Cruises from Miami to Rome Cruises from Miami to Bridgetown Cruises from Miami to Panama City Cruises from Miami to Barcelona Cruises from Miami to Miami Cruises from Miami to London Cruises from Montreal to New York Cruises from New York to New York Cruises from New York to London Cruises from Papeete to Papeete Cruises from Quito to Guayaquil Cruises from Quito to Quito Cruises from Rio de Janeiro to Rio de Janeiro Cruises from Rio de Janeiro to Barcelona Cruises from Rome to London Cruises from Rome to Lisbon Cruises from Rome to Miami Cruises from Rome to Barcelona Cruises from Rome to Fort Lauderdale Cruises from Rome to Rome Cruises from San Antonio to Buenos Aires Cruises from San Juan to San Juan Cruises from Santiago to Santiago Cruises from Sao Paulo to Sao Paulo

Country Routes

Cruises from Peru to Argentina Cruises from USA to Portugal Cruises from USA to Germany Cruises from Italy to England Cruises from Germany to England Cruises from France to Spain Cruises from Portugal to England Cruises from Puerto Rico to USA Cruises from France to Brazil Cruises from France to USA Cruises from England to Canada Cruises from England to Germany Cruises from Brazil to Spain Cruises from USA to Puerto Rico Cruises from Canada to England Cruises from Argentina to Brazil Cruises from Argentina to Chile Cruises from Brazil to Italy Cruises from Argentina to USA Cruises from Barbados to USA Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Denmark Cruises from England to Italy Cruises from England to Spain Cruises from England to USA Cruises from France to Italy Cruises from French Polynesia to USA Cruises from Italy to Brazil Cruises from Italy to France Cruises from Italy to Portugal Cruises from Italy to Spain Cruises from Italy to USA Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Peru to Ecuador Cruises from Portugal to Italy Cruises from Portugal to Spain Cruises from Portugal to USA Cruises from Spain to France Cruises from Spain to Italy Cruises from Spain to Portugal Cruises from Spain to USA Cruises from USA to Argentina Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from England to Portugal Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Holland Cruises from USA to Italy Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Peru Cruises from USA to Spain

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises Hurtigruten South America Cruises MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

South America Tours

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