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341 Cruises (1,746 Cruise Departures)
9 Day Galapagos Voyage: Pirates & Darwin - Premium Adventure with Exodus Adventure Travels
New ReleaseCruise

9 Days (8 Nights) Quito to Quito
Departures: Aug 2024 to Dec 2024
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador
Exclusive Savings
Save 326
From 15,974
View Trip
7 Day Galapagos Explorer: Central Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jun 2024 to Dec 2024
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save 1,977
From 4,642
View Trip
5 Day South America with MSC Cruises
Cruise

5 Days (4 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 20 March 2025
Countries Visited: Brazil
Early Booking Offer
INSIDE
$916
OCEANVIEW
$1,045
BALCONY
$1,194
SUITE
$1,540
From 916
View Trip
11 Day Brazilian Brilliance with Oceania Cruises
Cruise

11 Days (10 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 07 March 2026
Countries Visited: Argentina, Uruguay, Brazil
Exclusive Deal
INSIDE
$5,124
OCEANVIEW
$5,807
BALCONY
$6,421
SUITE
$8,955
Save 2,036
From 5,124
View Trip
9 Day Lima to Valparaiso with Silversea
Cruise

9 Days (8 Nights) Lima to Valparaiso
Cruise Line: Silversea
Ship: Silver Wind
Departure: 10 November 2024
Countries Visited: Peru, Chile
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
$7,326
BALCONY
$10,593
SUITE
-
From 7,326
View Trip
8 Day Galápagos - South & East Islands aboard the Eden with G Adventures
Cruise

8 Days (7 Nights) Quito to Quito
Operated By: G Adventures
Departures: May 2024 to Dec 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Deal
Save 1,601
From 4,618
View Trip
4 Day South America with MSC Cruises
Cruise

4 Days (3 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Nov 2024 to Dec 2024
Countries Visited: Brazil
Early Booking Offer
INSIDE
$697
OCEANVIEW
$777
BALCONY
$895
SUITE
$1,470
From 697
View Trip
8 Day Lima to Panama City with Silversea
Cruise

8 Days (7 Nights) Lima to Panama City
Cruise Line: Silversea
Ship: Silver Ray
Departure: 04 January 2025
Countries Visited: Peru, Ecuador, Panama
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$4,158
From 4,158
View Trip
15 Day Patagonia & Argentina Cruise with Celebrity Cruises
Cruise

15 Days (14 Nights) Buenos Aires to Buenos Aires
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: Dec 2025 to Feb 2026
Countries Visited: Argentina, Uruguay, Falkland Islands, Chile
Exclusive DealExclusive Offer
INSIDE
$2,791
OCEANVIEW
$3,039
BALCONY
$3,696
SUITE
$9,661
Save 4,602
From 2,791
View Trip
13 Day Highlights of Peru with Galápagos Legend East Cruise with Trafalgar
Tour + Cruise

13 Days Lima to Quito
Operated By: Trafalgar
Departures: Aug 2024 to Nov 2024
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador
Exclusive Savings
From 12,389
View Trip
15 Day Peru & Galapagos by Yacht with Collette
Tour + Cruise

15 Days Lima to Quito
Operated By: Collette
Departures: Sep 2024 to Mar 2025
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Bucket List Savings Sale
Save 1,997
From 9,702
View Trip
12 Day Lautoka to Tahiti with Silversea
Cruise

12 Days (11 Nights) Lautoka to Tahiti
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 29 September 2025
Countries Visited: Fiji, Cook Islands, Tonga, French Polynesia
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$22,473
BALCONY
$25,641
SUITE
$38,709
From 22,473
View Trip
17 Day Absolute Galapagos (Grand Daphne) with Intrepid Travel
Cruise

17 Days (16 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Sep 2024 to Dec 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 395
From 18,486
View Trip
13 Day Beautiful Brazil & Beyond with Oceania Cruises
Cruise

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 24 March 2025
Countries Visited: Argentina, Uruguay, Brazil
Cabin Upgrade Offer
INSIDE
$5,987
OCEANVIEW
$6,898
BALCONY
$7,512
SUITE
$8,274
From 5,987
View Trip
15 Day Season Of Samba with Regent Seven Seas
Cruise

15 Days (14 Nights) Bridgetown to Rio de Janeiro
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 03 December 2025
Countries Visited: Barbados, Saint Vincent, Trinidad and Tobago, French Guiana (+1 more), Brazil
Land Package Credit
INSIDE
-
OCEANVIEW
-
BALCONY
$13,761
SUITE
$15,533
Save 8,269
From 13,761
View Trip
15 Day Cape Horn & Strait of Magellan with Princess
Cruise

15 Days (14 Nights) Buenos Aires to Santiago
Cruise Line: Princess
Ship: Sapphire Princess
Departures: Feb 2025 to Mar 2025
Countries Visited: Argentina, Uruguay, Falkland Islands, Chile
INSIDE
$2,938
OCEANVIEW
$3,039
BALCONY
$5,611
SUITE
$6,093
From 2,938
View Trip
7 Day Galapagos Express - Central & West Islands aboard the Archipel I with Explore!
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: Explore!
Departures: Jun 2024 to Dec 2024
Trip Styles: Small Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 152
From 7,428
View Trip
25 Day Palms To Penguins with Oceania Cruises
Cruise

25 Days (24 Nights) Rio de Janeiro to San Antonio
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 22 January 2026
Countries Visited: Brazil, Uruguay, Argentina, Falkland Islands (+1 more), Chile
Exclusive Deal
INSIDE
$11,801
OCEANVIEW
$13,405
BALCONY
$15,009
SUITE
$21,493
Save 2,089
From 11,801
View Trip
8 Day Galapagos Southern with Celebrity Cruises
Cruise

8 Days (7 Nights) Baltra Island to Baltra Island
Cruise Line: Celebrity Cruises
Ship: Celebrity Xpedition
Departures: May 2024 to Dec 2025
Countries Visited: Galapagos
Exclusive Deal
INSIDE
-
OCEANVIEW
$7,892
BALCONY
-
SUITE
$9,132
Save 4,749
From 7,892
View Trip
10 Day Galapagos - Central, South & East Islands aboard the Archipel I with Explore!
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: Explore!
Departures: May 2024 to Dec 2025
Trip Styles: Small Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 226
From 10,751
View Trip
9 Day South America with MSC Cruises
Cruise

9 Days (8 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 27 December 2024
Countries Visited: Brazil
Early Booking Offer
INSIDE
$3,338
OCEANVIEW
$3,487
BALCONY
$3,784
SUITE
$4,694
From 3,338
View Trip
13 Day Patagonia: Edge of the World with Collette
Tour + Cruise

13 Days Buenos Aires to Buenos Aires
Operated By: Collette
Departures: Oct 2024 to Mar 2025
Trip Styles: Adventure, Coach, Small Group, Cruise, Scenic
Countries Visited: Argentina, Chile
Bucket List Savings Sale
Save 2,323
From 9,321
View Trip
12 Day Crossing the Equator: Barbados to Brazil with Scenic
Cruise

12 Days (11 Nights) Bridgetown to Rio de Janeiro
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 05 November 2024
Countries Visited: Brazil, French Guiana, Barbados
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$6,579
SUITE
$10,207
Save 8,566
From 6,579
View Trip
9 Day South America with MSC Cruises
Cruise

9 Days (8 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Dec 2024 to Jan 2025
Countries Visited: Brazil, Argentina, Uruguay
Early Booking Offer
INSIDE
$1,596
OCEANVIEW
$1,606
BALCONY
$1,903
SUITE
$3,348
From 1,596
View Trip
7 Day Galápagos - North & Central Islands aboard the Eden with G Adventures
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: G Adventures
Departures: May 2024 to Dec 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Deal
Save 1,260
From 4,561
View Trip
14 Day Highlights Of South America – Land And Sea Expedition with Hurtigruten
Tour + Cruise

14 Days Colon to Lima
Operated By: Hurtigruten
Ship: MS Fram
Departure: 06 October 2024
Countries Visited: Panama, Ecuador, Peru
Exclusive Deal
INSIDE
$19,313
OCEANVIEW
$20,598
BALCONY
-
SUITE
$22,835
Save 2,357
From 19,313
View Trip
7 Day Galapagos Express - Central, South & East Islands aboard the Archipel I with Explore!
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: Explore!
Departures: May 2024 to Dec 2025
Trip Styles: Small Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 155
From 7,428
View Trip
10 Day South America with MSC Cruises
Cruise

10 Days (9 Nights) Salvador to Salvador
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 29 December 2024
Countries Visited: Brazil
Early Booking Offer
INSIDE
$3,498
OCEANVIEW
$3,647
BALCONY
$3,944
SUITE
$8,498
From 3,498
View Trip
4 Day South America with MSC Cruises
Cruise

4 Days (3 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Mar 2025 to Apr 2025
Countries Visited: Brazil
Early Booking Offer
INSIDE
$767
OCEANVIEW
$866
BALCONY
$975
SUITE
$1,242
From 767
View Trip
15 Day Cape Horn & Strait of Magellan with Princess
Cruise

15 Days (14 Nights) Santiago to Buenos Aires
Cruise Line: Princess
Ship: Sapphire Princess
Departure: 21 February 2025
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
INSIDE
$2,751
OCEANVIEW
$2,850
BALCONY
$5,206
SUITE
$5,820
From 2,751
View Trip
Results: 121-150 of 341

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South & Central America Cruises

Amazon Cruises Antarctica Cruises Argentina Cruises Bahamas Cruises Barbados Cruises Bermunda Cruises Brazil Cruises Cape Horn Cruises Caribbean Cruises Central America Cruises Chile Cruises Ecuador Cruises Falkland Island Cruises Falkland Islands Cruises France Cruises Galapagos Cruises Mexico Cruises Morocco Cruises Panama Cruises Panama Cruises Patagonia Cruises Peru Cruises Portugal Cruises South America Cruises South Georgia Island Cruises Spain Cruises Uruguay Cruises

Travel Styles

Coach Tours Locally Guided Tours Luxury Cruises Short Cruise Breaks Wildlife Tours

Cities

Barcelona Bridgetown Buenos Aires Colon Lima Lisbon Manaus Marseille Papeete Quito Rio de Janeiro San Antonio Santiago Santiago Sao Paulo

Routes

Cruises from Barcelona to Fort Lauderdale Cruises from Barcelona to Lisbon Cruises from Barcelona to London Cruises from Barcelona to Rome Cruises from Barcelona to Barcelona Cruises from Barcelona to Miami Cruises from Bridgetown to Miami Cruises from Bridgetown to Bridgetown Cruises from Buenos Aires to San Antonio Cruises from Buenos Aires to Rio de Janeiro Cruises from Buenos Aires to Buenos Aires Cruises from Dover to Dover Cruises from Fort Lauderdale to Los Angeles Cruises from Fort Lauderdale to London Cruises from Fort Lauderdale to Barcelona Cruises from Fort Lauderdale to Fort Lauderdale Cruises from Fort Lauderdale to San Diego Cruises from Genoa to Genoa Cruises from Hamburg to London Cruises from Hamburg to Hamburg Cruises from Lima to Buenos Aires Cruises from Lima to Quito Cruises from Lisbon to Lisbon Cruises from Lisbon to London Cruises from Lisbon to Miami Cruises from Lisbon to Barcelona Cruises from Lisbon to Rome Cruises from London to Hamburg Cruises from London to Barcelona Cruises from London to Fort Lauderdale Cruises from London to Copenhagen Cruises from London to Rome Cruises from London to London Cruises from London to Lisbon Cruises from London to New York Cruises from Los Angeles to Miami Cruises from Los Angeles to Fort Lauderdale Cruises from Los Angeles to Los Angeles Cruises from Marseille to Marseille Cruises from Miami to San Juan Cruises from Miami to Los Angeles Cruises from Miami to Rome Cruises from Miami to Bridgetown Cruises from Miami to Panama City Cruises from Miami to Barcelona Cruises from Miami to Miami Cruises from Miami to London Cruises from Montreal to New York Cruises from New York to New York Cruises from New York to London Cruises from Papeete to Papeete Cruises from Quito to Guayaquil Cruises from Quito to Quito Cruises from Rio de Janeiro to Rio de Janeiro Cruises from Rio de Janeiro to Barcelona Cruises from Rome to London Cruises from Rome to Lisbon Cruises from Rome to Miami Cruises from Rome to Barcelona Cruises from Rome to Fort Lauderdale Cruises from Rome to Rome Cruises from San Antonio to Buenos Aires Cruises from San Juan to San Juan Cruises from Santiago to Santiago Cruises from Sao Paulo to Sao Paulo

Country Routes

Cruises from Peru to Argentina Cruises from USA to Portugal Cruises from USA to Germany Cruises from Italy to England Cruises from Germany to England Cruises from France to Spain Cruises from Portugal to England Cruises from Puerto Rico to USA Cruises from France to Brazil Cruises from France to USA Cruises from England to Canada Cruises from England to Germany Cruises from Brazil to Spain Cruises from USA to Puerto Rico Cruises from Canada to England Cruises from Argentina to Brazil Cruises from Argentina to Chile Cruises from Brazil to Italy Cruises from Argentina to USA Cruises from Barbados to USA Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Denmark Cruises from England to Italy Cruises from England to Spain Cruises from England to USA Cruises from France to Italy Cruises from French Polynesia to USA Cruises from Italy to Brazil Cruises from Italy to France Cruises from Italy to Portugal Cruises from Italy to Spain Cruises from Italy to USA Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Peru to Ecuador Cruises from Portugal to Italy Cruises from Portugal to Spain Cruises from Portugal to USA Cruises from Spain to France Cruises from Spain to Italy Cruises from Spain to Portugal Cruises from Spain to USA Cruises from USA to Argentina Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from England to Portugal Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Holland Cruises from USA to Italy Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Peru Cruises from USA to Spain

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises Hurtigruten South America Cruises MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

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