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342 Cruises (1,747 Cruise Departures)
10 Day Galapagos - Central, South & East Islands aboard the Archipel I with Explore!
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: Explore!
Departures: May 2024 to Dec 2025
Trip Styles: Small Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 226
From 10,751
View Trip
15 Day Cape Horn & Strait of Magellan with Princess
Cruise

15 Days (14 Nights) Buenos Aires to Santiago
Cruise Line: Princess
Ship: Sapphire Princess
Departures: Feb 2025 to Mar 2025
Countries Visited: Argentina, Uruguay, Falkland Islands, Chile
INSIDE
$2,938
OCEANVIEW
$3,039
BALCONY
$5,611
SUITE
$6,093
From 2,938
View Trip
13 Day Highlights of Peru with Galápagos Legend East Cruise with Trafalgar
Tour + Cruise

13 Days Lima to Quito
Operated By: Trafalgar
Departures: Aug 2024 to Nov 2024
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador
Exclusive Savings
From 12,389
View Trip
10 Day Galápagos - North, Central, & South Islands aboard the Eden with G Adventures
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: G Adventures
Departures: May 2024 to Dec 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Deal
Save 2,188
From 6,103
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Dec 2024 to Mar 2025
Countries Visited: Brazil
Early Booking Offer
INSIDE
$1,307
OCEANVIEW
$1,485
BALCONY
$1,733
SUITE
$2,762
From 1,307
View Trip
9 Day Lima to Valparaiso with Silversea
Cruise

9 Days (8 Nights) Lima to Valparaiso
Cruise Line: Silversea
Ship: Silver Ray
Departure: 01 February 2025
Countries Visited: Chile, Peru
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$7,672
From 7,672
View Trip
6 Day Galapagos Encounter: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise

6 Days (5 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jun 2024 to Dec 2024
Trip Styles: Group, Cruise, Island Hopping, Short Break, Wildlife
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save 1,557
From 3,693
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departures: Jun 2024 to Mar 2026
Countries Visited: Ecuador, Galapagos
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
$15,642
SUITE
$18,513
From 15,642
View Trip
8 Day Galápagos – Central and East Islands aboard the Reina Silvia Voyager (Cruise Only) with G Adventures
Cruise

8 Days (7 Nights) Baltra Island to Baltra Island
Operated By: G Adventures
Departures: Jun 2024 to Dec 2025
Trip Styles: Small Group, Cruise, Island Hopping, Wildlife
Countries Visited: Galapagos
Exclusive Deal
Save 2,446
From 6,756
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6 Day Galapagos Encounter: Central Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise

6 Days (5 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: May 2024 to Dec 2024
Trip Styles: Group, Cruise, Island Hopping, Short Break, Wildlife
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save 1,557
From 3,693
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Salvador to Salvador
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Dec 2024 to Mar 2025
Countries Visited: Brazil
Early Booking Offer
INSIDE
$1,307
OCEANVIEW
$1,485
BALCONY
$1,733
SUITE
$4,881
From 1,307
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departure: 01 November 2025
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$17,919
SUITE
$26,730
From 17,919
View Trip
10 Day South America with MSC Cruises
Cruise

10 Days (9 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 28 February 2025
Countries Visited: Argentina, Uruguay, Brazil
Early Booking Offer
INSIDE
$1,983
OCEANVIEW
$2,241
BALCONY
$2,558
SUITE
$4,072
From 1,983
View Trip
15 Day Cape Horn & Strait of Magellan with Princess
Cruise

15 Days (14 Nights) Santiago to Buenos Aires
Cruise Line: Princess
Ship: Sapphire Princess
Departure: 21 February 2025
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
INSIDE
$2,751
OCEANVIEW
$2,850
BALCONY
$5,206
SUITE
$5,820
From 2,751
View Trip
8 Day Pure Galapagos (Grand Daphne) with Intrepid Travel
Cruise

8 Days (7 Nights) Baltra Island to Baltra Island
Operated By: Intrepid Travel
Departures: Jun 2024 to Dec 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save 2,660
From 6,333
View Trip
8 Day Galapagos: Wildlife Wonderland with Tauck
Cruise

8 Days (7 Nights) Quito to Guayaquil
Operated By: Tauck
Departures: Jun 2025 to Aug 2025
Trip Styles: Group, Cruise, Family, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
From 12,140
View Trip
10 Day Classic Galapagos: South Eastern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: May 2024 to Dec 2024
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save 3,114
From 7,206
View Trip
10 Day Galápagos – Central and East Islands aboard the Reina Silvia Voyager with G Adventures
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: G Adventures
Departures: May 2024 to Dec 2025
Trip Styles: Small Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Deal
Save 2,678
From 7,424
View Trip
30 Day Best of South America with Amazon and Galapagos Cruises with APT
Tour + Cruise

30 Days Santiago to Guayaquil
Operated By: APT
Ship: Delfin III
Departures: Apr 2025 to Sep 2025
Trip Styles: Coach, Group, Cruise, River Cruise, Island Hopping, Scenic
Countries Visited: Chile, Argentina, Brazil, Peru (+2 more), Ecuador, Galapagos
Exclusive Deal
Save 2,739
From 39,656
View Trip
12 Day Wonders of the Galápagos & Machu Picchu with Abercrombie & Kent
New ReleaseTour + Cruise

12 Days Guayaquil to Lima
Operated By: Abercrombie & Kent
Departures: Jul 2024 to Nov 2024
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Ecuador, Galapagos, Peru
Exclusive Solo Offer
From 26,490
View Trip
15 Day Chilean Fjords – Discovering The Heart Of Patagonia with Hurtigruten
Cruise

15 Days (14 Nights) Valparaiso to Buenos Aires
Cruise Line: Hurtigruten
Ship: MS Fridtjof Nansen
Departure: 17 October 2025
Countries Visited: Chile, Argentina
Exclusive Deal
INSIDE
-
OCEANVIEW
$18,046
BALCONY
$21,097
SUITE
$24,788
Save 5,586
From 18,046
View Trip
10 Day Heart Of The Amazon with Seabourn
Cruise

10 Days (9 Nights) Manaus to Manaus
Cruise Line: Seabourn
Ship: Venture
Departure: 12 October 2025
Countries Visited: Brazil
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$15,197
SUITE
$29,334
From 15,197
View Trip
13 Day Rhythms of the Brazilian Coastline with Scenic
Cruise

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 22 March 2025
Countries Visited: Argentina, Uruguay, Brazil
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$12,271
SUITE
$18,706
Save 5,624
From 12,271
View Trip
13 Day Chilean Fjords & Scenic Shores with Viking Cruises
Cruise

13 Days (12 Nights) Santiago to Buenos Aires
Cruise Line: Viking Cruises
Ships: Viking Octantis, Viking Polaris
Departures: Nov 2024 to Oct 2025
Countries Visited: Chile, Argentina
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$13,855
SUITE
$19,795
Save 1,140
From 13,855
View Trip
13 Day Treasures of Galapagos: Western & Central Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise

13 Days (12 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jun 2024 to Dec 2024
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save 4,218
From 9,701
View Trip
10 Day Galapagos - Central, West & East Islands aboard the Archipel I with Explore!
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: Explore!
Departures: Jun 2024 to Dec 2025
Trip Styles: Small Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 252
From 10,751
View Trip
10 Day Galapagos Encounter (Itinerary A) with Exodus Adventure Travels
Cruise

10 Days (9 Nights) Quito to Guayaquil
Departures: Jun 2024 to Dec 2025
Trip Styles: Small Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 250
From 11,250
View Trip
10 Day Galapagos Encounter (Itinerary B) with Exodus Adventure Travels
Cruise

10 Days (9 Nights) Quito to Guayaquil
Departures: Aug 2024 to Dec 2025
Trip Styles: Small Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 250
From 11,250
View Trip
9 Day Lima to Valparaiso with Silversea
Cruise

9 Days (8 Nights) Lima to Valparaiso
Cruise Line: Silversea
Ship: Silver Wind
Departure: 10 November 2024
Countries Visited: Peru, Chile
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
$7,326
BALCONY
$10,593
SUITE
-
From 7,326
View Trip
19 Day Around Cape Horn with Oceania Cruises
Cruise

19 Days (18 Nights) Buenos Aires to Lima
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 03 February 2026
Countries Visited: Argentina, Uruguay, Falkland Islands, Chile (+1 more), Peru
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$10,489
SUITE
$16,152
Save 2,081
From 10,489
View Trip
Results: 31-60 of 342

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South & Central America Cruises

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Travel Styles

Coach Tours Luxury Cruises Short Cruise Breaks Wildlife Tours

Cities

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Routes

Cruises from Barcelona to Fort Lauderdale Cruises from Barcelona to Lisbon Cruises from Barcelona to London Cruises from Barcelona to Rome Cruises from Barcelona to Barcelona Cruises from Barcelona to Miami Cruises from Bridgetown to Miami Cruises from Bridgetown to Bridgetown Cruises from Buenos Aires to San Antonio Cruises from Buenos Aires to Rio de Janeiro Cruises from Buenos Aires to Buenos Aires Cruises from Dover to Dover Cruises from Fort Lauderdale to Los Angeles Cruises from Fort Lauderdale to London Cruises from Fort Lauderdale to Barcelona Cruises from Fort Lauderdale to Fort Lauderdale Cruises from Fort Lauderdale to San Diego Cruises from Genoa to Genoa Cruises from Hamburg to London Cruises from Hamburg to Hamburg Cruises from Lima to Buenos Aires Cruises from Lima to Quito Cruises from Lisbon to Lisbon Cruises from Lisbon to London Cruises from Lisbon to Miami Cruises from Lisbon to Barcelona Cruises from Lisbon to Rome Cruises from London to Hamburg Cruises from London to Barcelona Cruises from London to Fort Lauderdale Cruises from London to Copenhagen Cruises from London to Rome Cruises from London to London Cruises from London to Lisbon Cruises from London to New York Cruises from Los Angeles to Miami Cruises from Los Angeles to Fort Lauderdale Cruises from Los Angeles to Los Angeles Cruises from Malaga to Malaga Cruises from Marseille to Marseille Cruises from Miami to San Juan Cruises from Miami to Los Angeles Cruises from Miami to Rome Cruises from Miami to Bridgetown Cruises from Miami to Panama City Cruises from Miami to Barcelona Cruises from Miami to Miami Cruises from Miami to London Cruises from Montreal to New York Cruises from New York to New York Cruises from New York to London Cruises from Papeete to Papeete Cruises from Quito to Guayaquil Cruises from Quito to Quito Cruises from Rio de Janeiro to Rio de Janeiro Cruises from Rio de Janeiro to Barcelona Cruises from Rome to London Cruises from Rome to Lisbon Cruises from Rome to Miami Cruises from Rome to Barcelona Cruises from Rome to Fort Lauderdale Cruises from Rome to Rome Cruises from San Antonio to Buenos Aires Cruises from San Juan to San Juan Cruises from Santiago to Santiago Cruises from Sao Paulo to Sao Paulo

Country Routes

Cruises from Peru to Argentina Cruises from USA to Portugal Cruises from USA to Germany Cruises from Italy to England Cruises from Germany to England Cruises from France to Spain Cruises from Portugal to England Cruises from Puerto Rico to USA Cruises from France to Brazil Cruises from France to USA Cruises from England to Canada Cruises from England to Germany Cruises from Brazil to Spain Cruises from USA to Puerto Rico Cruises from Canada to England Cruises from Argentina to Brazil Cruises from Argentina to Chile Cruises from Brazil to Italy Cruises from Argentina to USA Cruises from Barbados to USA Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Denmark Cruises from England to Italy Cruises from England to Spain Cruises from England to USA Cruises from France to Italy Cruises from French Polynesia to USA Cruises from Italy to Brazil Cruises from Italy to France Cruises from Italy to Portugal Cruises from Italy to Spain Cruises from Italy to USA Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Peru to Ecuador Cruises from Portugal to Italy Cruises from Portugal to Spain Cruises from Portugal to USA Cruises from Spain to France Cruises from Spain to Italy Cruises from Spain to Portugal Cruises from Spain to USA Cruises from USA to Argentina Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from England to Portugal Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Holland Cruises from USA to Italy Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Peru Cruises from USA to Spain

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises Hurtigruten South America Cruises MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

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